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Gene Information
Gene symbol: SPIB
Gene name: Spi-B transcription factor (Spi-1/PU.1 related)
HGNC ID: 11242
Synonyms: SPI-B
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | HES1 | 1 hits |
| 2 | IL7R | 1 hits |
| 3 | KIT | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15494484 | At 5-8 wk of age, even in the absence of TCRbeta expression, CD4+ and CD4+CD8+ blasts appear spontaneously. |
| 2 | 15494484 | They mimic normal beta selection by up-regulating germline TCR-Calpha transcripts, CD2, and Bcl-xL and down-regulating Bcl-2. |
| 3 | 15494484 | However, they fail to down-regulate transcription factors HEB-alt and Hes1 and initially express aberrantly high levels of Spi-B, c-kit (CD117), and IL-7Ralpha. |