Ignet

Gene Information

Gene symbol: SRY

Gene name: sex determining region Y

HGNC ID: 11311

Synonyms: TDF

Related Genes

#	Gene Symbol	Number of hits
1	CEBPA	1 hits
2	CYP2B6	1 hits
3	EBP	1 hits
4	HMGB1	1 hits
5	IGF1	1 hits
6	INS	1 hits
7	LEF1	1 hits
8	SOX13	1 hits
9	TBP	1 hits
10	TBXAS1	1 hits
11	TCF7	1 hits

Related Sentences

#	PMID	Sentence
1	1618927	Identification of a core motif that is recognized by three members of the HMG class of transcriptional regulators: IRE-ABP, SRY, and TCF-1 alpha.
2	1618927	Insulin induces glyceraldehyde-3-phosphate dehydrogenase (GADPH) gene transcription in part by regulating one or more proteins that bind a cis-acting element, IRE-A.
3	1618927	Insulin regulates GAPDH gene transcription in a tissue-specific manner.
4	7547937	The structural features of the DNA complexed to SRY are remarkably similar, but not identical, to those of DNA complexed to the TATA-binding protein (TBP).
5	9646864	These include TATA-box-binding protein, integration host factor (IHF), high mobility group I(Y)[HMG I(Y)], and the HMG-box-containing proteins SRY and LEF-1.
6	9731699	IRE-ABP (insulin response element-A binding protein), an SRY-like protein, inhibits C/EBPalpha (CCAAT/enhancer-binding protein alpha)-stimulated expression of the sex-specific cytochrome P450 2C12 gene.
7	9731699	In primary hepatocytes, overexpression of an insulin response element-A binding protein (IRE-ABP), a member of the SRY family of high-mobility group (HMG) proteins, inhibits CCAAT/enhancer-binding protein alpha (C/EBPalpha)-mediated activation of the female-specific cytochrome P450 2C12 (CYP2C12) gene, but not the male-specific cytochrome P450 2C11 (CYP2C11) gene.
8	9731699	Taken together, our findings suggest that SRY-like proteins can bind to a subset of sequences recognized by the C/EBP family of DNA-binding proteins and modulate gene transcription in a context-specific manner.
9	9731699	IRE-ABP (insulin response element-A binding protein), an SRY-like protein, inhibits C/EBPalpha (CCAAT/enhancer-binding protein alpha)-stimulated expression of the sex-specific cytochrome P450 2C12 gene.
10	9731699	In primary hepatocytes, overexpression of an insulin response element-A binding protein (IRE-ABP), a member of the SRY family of high-mobility group (HMG) proteins, inhibits CCAAT/enhancer-binding protein alpha (C/EBPalpha)-mediated activation of the female-specific cytochrome P450 2C12 (CYP2C12) gene, but not the male-specific cytochrome P450 2C11 (CYP2C11) gene.
11	9731699	Taken together, our findings suggest that SRY-like proteins can bind to a subset of sequences recognized by the C/EBP family of DNA-binding proteins and modulate gene transcription in a context-specific manner.
12	9731699	IRE-ABP (insulin response element-A binding protein), an SRY-like protein, inhibits C/EBPalpha (CCAAT/enhancer-binding protein alpha)-stimulated expression of the sex-specific cytochrome P450 2C12 gene.
13	9731699	In primary hepatocytes, overexpression of an insulin response element-A binding protein (IRE-ABP), a member of the SRY family of high-mobility group (HMG) proteins, inhibits CCAAT/enhancer-binding protein alpha (C/EBPalpha)-mediated activation of the female-specific cytochrome P450 2C12 (CYP2C12) gene, but not the male-specific cytochrome P450 2C11 (CYP2C11) gene.
14	9731699	Taken together, our findings suggest that SRY-like proteins can bind to a subset of sequences recognized by the C/EBP family of DNA-binding proteins and modulate gene transcription in a context-specific manner.
15	10854791	SOX13 is the member of the SOX (Sry related HMG BOX) family of transcription factors which encodes the type-1 diabetes autoantigen, ICA12, and is expressed in a number of tissues including pancreatic islets and arterial walls.
16	10871192	Sex-determining region Y-related protein SOX13 is a diabetes autoantigen expressed in pancreatic islets.
17	15469275	We demonstrate the applicability of this approach to HMG-box proteins and contrast the results obtained for nonspecific DNA binding of the A-box of HMGB-1 (HMGB-1A) with sequence-specific DNA binding of the related SRY protein.
18	16734553	Minimally invasive sampling of transdermal body fluid for the purpose of measuring insulin-like growth factor-I during exercise training.
19	16734553	Insulin-like growth factor-I (IGF-I) is a ubiquitous hormone that is secreted in both an endocrine and an autocrine/paracrine manner.
20	16734553	The purpose of this study was to compare IGF-I in serum versus IGF-I in TDF before and after 8 weeks of physical training.
21	16734553	Total TDF IGF-I was significantly lower than serum IGF-I both before (TDF, 91 +/- 6 ng/mL; serum, 375 +/- 17 ng/mL) and after (TDF, 83 +/- 5 ng/mL; serum, 363 +/- 19 ng/mL) the exercise training.
22	16734553	Serum and TDF IGF-I values were not significantly different pre- to post-training.
23	16734553	Serum and TDF IGF-I levels were significantly correlated pre-training (r = 0.41), but not post-training (r = 0.34).
24	16734553	Minimally invasive sampling of transdermal body fluid for the purpose of measuring insulin-like growth factor-I during exercise training.
25	16734553	Insulin-like growth factor-I (IGF-I) is a ubiquitous hormone that is secreted in both an endocrine and an autocrine/paracrine manner.
26	16734553	The purpose of this study was to compare IGF-I in serum versus IGF-I in TDF before and after 8 weeks of physical training.
27	16734553	Total TDF IGF-I was significantly lower than serum IGF-I both before (TDF, 91 +/- 6 ng/mL; serum, 375 +/- 17 ng/mL) and after (TDF, 83 +/- 5 ng/mL; serum, 363 +/- 19 ng/mL) the exercise training.
28	16734553	Serum and TDF IGF-I values were not significantly different pre- to post-training.
29	16734553	Serum and TDF IGF-I levels were significantly correlated pre-training (r = 0.41), but not post-training (r = 0.34).
30	16734553	Minimally invasive sampling of transdermal body fluid for the purpose of measuring insulin-like growth factor-I during exercise training.
31	16734553	Insulin-like growth factor-I (IGF-I) is a ubiquitous hormone that is secreted in both an endocrine and an autocrine/paracrine manner.
32	16734553	The purpose of this study was to compare IGF-I in serum versus IGF-I in TDF before and after 8 weeks of physical training.
33	16734553	Total TDF IGF-I was significantly lower than serum IGF-I both before (TDF, 91 +/- 6 ng/mL; serum, 375 +/- 17 ng/mL) and after (TDF, 83 +/- 5 ng/mL; serum, 363 +/- 19 ng/mL) the exercise training.
34	16734553	Serum and TDF IGF-I values were not significantly different pre- to post-training.
35	16734553	Serum and TDF IGF-I levels were significantly correlated pre-training (r = 0.41), but not post-training (r = 0.34).
36	16734553	Minimally invasive sampling of transdermal body fluid for the purpose of measuring insulin-like growth factor-I during exercise training.
37	16734553	Insulin-like growth factor-I (IGF-I) is a ubiquitous hormone that is secreted in both an endocrine and an autocrine/paracrine manner.
38	16734553	The purpose of this study was to compare IGF-I in serum versus IGF-I in TDF before and after 8 weeks of physical training.
39	16734553	Total TDF IGF-I was significantly lower than serum IGF-I both before (TDF, 91 +/- 6 ng/mL; serum, 375 +/- 17 ng/mL) and after (TDF, 83 +/- 5 ng/mL; serum, 363 +/- 19 ng/mL) the exercise training.
40	16734553	Serum and TDF IGF-I values were not significantly different pre- to post-training.
41	16734553	Serum and TDF IGF-I levels were significantly correlated pre-training (r = 0.41), but not post-training (r = 0.34).