Ignet

Gene Information

Gene symbol: ST3GAL4

Gene name: ST3 beta-galactoside alpha-2,3-sialyltransferase 4

HGNC ID: 10864

Synonyms: STZ, SAT3, FLJ11867

Related Genes

#	Gene Symbol	Number of hits
1	AAVS1	1 hits
2	ABCB11	1 hits
3	ABHD12	1 hits
4	ABO	1 hits
5	ASGR1	1 hits
6	ATP8B1	1 hits
7	CD276	1 hits
8	CDH6	1 hits
9	EFNA1	1 hits
10	EPHA2	1 hits
11	FADS1	1 hits
12	FADS2	1 hits
13	FUT2	1 hits
14	GCKR	1 hits
15	GGT1	1 hits
16	GPLD1	1 hits
17	GSTT1	1 hits
18	GSTT2	1 hits
19	HNF1A	1 hits
20	INS	1 hits
21	JMJD1C	1 hits
22	MICAL3	1 hits
23	MLXIPL	1 hits
24	NUDT6	1 hits
25	PCNA	1 hits
26	PDGFB	1 hits
27	PDX1	1 hits
28	PNPLA3	1 hits
29	PPP1R3B	1 hits
30	RORA	1 hits
31	SAT2	1 hits
32	SLC2A2	1 hits
33	SLC38A3	1 hits
34	STAT4	1 hits
35	TGFB1	1 hits
36	TNF	1 hits
37	TRIB1	1 hits
38	ZNF827	1 hits

Related Sentences

#	PMID	Sentence
1	6389231	The effects of adrenergic blockers on the glucagon response to insulin hypoglycemia were investigated in diabetic (10-15 days poststreptozocin [STZ] injection) and age-matched control rats. alpha-(Phentolamine nonspecific but predominantly alpha 1), alpha 2-(yohimbine), or beta-(propranolol) adrenergic blockers alone or in combination did not affect plasma glucose levels or plasma glucagon concentrations, in the basal state, in either control or diabetic rats.
2	8094359	Evaluations of glomerular mRNA levels encoding for PCNA, TNF-alpha, PDGF-A and -B chains, TGF-beta, IGF-I, bFGF, and EGF were made at 4, 12, and 24 wk after injection of STZ in Sprague-Dawley rats.
3	8094359	The mRNA levels for PCNA, TNF-alpha, PDGF-B chain, TGF-beta, and bFGF increased with age in STZ-induced diabetic rats.
4	8094359	At 24 wk after STZ injection, mRNA levels for PCNA, TNF-alpha, PDGF-B chain, TGF-beta, and bFGF were increased 3.8-fold, (P < 0.01), 4.2-fold (P < 0.01), 4.0-fold (P < 0.01), 5.2-fold (P < 0.001), and 3.6-fold (P < 0.01), respectively, in the glomeruli of diabetic rats when compared with control rats.
5	8094359	In contrast, mRNA levels for IGF-I, PDGF-A chain, and EGF were not altered in glomeruli from diabetic and control rats throughout the experimental period.
6	8094359	Insulin treatment partially ameliorated the increase in mRNA levels for PCNA, TNF-alpha, PDGF-B chain, TGF-beta, and bFGF in the glomeruli of diabetic rats.
7	11798158	SAT3, the more abundant system A mRNA isoform present in liver, is restricted to perivenous hepatocytes and is also increased following this treatment but to a much lesser extent than SAT2 mRNA.
8	11798158	A pharmacological dose of glucagon also increased both SAT2 and SAT3 mRNA levels in liver while SN1 mRNA levels remained unaffected.
9	11798158	SAT3, the more abundant system A mRNA isoform present in liver, is restricted to perivenous hepatocytes and is also increased following this treatment but to a much lesser extent than SAT2 mRNA.
10	11798158	A pharmacological dose of glucagon also increased both SAT2 and SAT3 mRNA levels in liver while SN1 mRNA levels remained unaffected.
11	18253862	This study was conducted to evaluate whether pdx-1 gene delivered by adeno-associated virus (AAV) could induce autologous liver cells to differentiate into insulin-producing cells and to explore the origin of these cells.
12	18253862	Here we used 4 x 10e(11) AAV to deliver pdx-1 to STZ-induced diabetic rats via the portal vein.
13	18253862	Immunofluorescent staining showed more insulin-positive cells, which had similar morphology with hepatic oval stem cells and were positive for hepatic oval stem cell markers, Thy-1 and cytokeratin 19 (ck19).
14	18253862	Our data indicated that rat hepatic oval stem cells were differentiated into bioactive insulin-producing cells by AAV-pdx-1 delivery in diabetic rats, with promoted expression of some transcription factors necessary for beta cell development and function.
15	22001757	We identified 69 candidate genes, including genes involved in biliary transport (ATP8B1 and ABCB11), glucose, carbohydrate and lipid metabolism (FADS1, FADS2, GCKR, JMJD1C, HNF1A, MLXIPL, PNPLA3, PPP1R3B, SLC2A2 and TRIB1), glycoprotein biosynthesis and cell surface glycobiology (ABO, ASGR1, FUT2, GPLD1 and ST3GAL4), inflammation and immunity (CD276, CDH6, GCKR, HNF1A, HPR, ITGA1, RORA and STAT4) and glutathione metabolism (GSTT1, GSTT2 and GGT), as well as several genes of uncertain or unknown function (including ABHD12, EFHD1, EFNA1, EPHA2, MICAL3 and ZNF827).