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Gene Information
Gene symbol: STAMBP
Gene name: STAM binding protein
HGNC ID: 16950
Synonyms: AMSH
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CARTPT | 1 hits |
| 2 | MC3R | 1 hits |
| 3 | MC4R | 1 hits |
| 4 | POMC | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 1314697 | In the present study, binding of DAB389-MSH to melanotropin receptors in biopsy specimens of human and mouse melanoma metastases was assessed by measuring its ability to inhibit binding of a radiolabeled, superpotent analogue of alpha-MSH (125I-[Nle4,D-Phe7]-alpha-MSH; 125I-NDP-MSH) and comparing its potency in this system with those of the established ligands NDP-MSH and alpha-MSH. |
| 2 | 1314697 | Taken together, these results suggest that NDP-MSH, alpha-MSH, and DAB389-MSH bind to a common melanotropin receptor in human metastatic melanoma cells. |
| 3 | 9096167 | In vitro, in heterologous cells expressing either rat MC3-R or MC4-R, the major MCR subtypes expressed in brain, SHU-9119 showed no intrinsic agonism, but it inhibited alpha-MSH-induced cAMP accumulation (IC50 = 0.48 +/- 0.19 and 0.41 +/- 0.28 nM, respectively) and [125I]-[Nle4,DPhe7]-alpha-MSH binding (IC50 = 1.0 +/- 0.1 and 0.9 +/- 0.3 nM, respectively). |
| 4 | 17228084 | Interestingly, ageing does not significantly alter hypothalamic mRNA levels of important anorexigens such as CART and aMSH. |