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Gene Information

Gene symbol: TBL1XR1

Gene name: transducin (beta)-like 1 X-linked receptor 1

HGNC ID: 29529

Synonyms: IRA1, FLJ12894, TBLR1, C21, DC42

Related Genes

# Gene Symbol Number of hits
1 BBS9 1 hits
2 NCOR1 1 hits
3 TBL1X 1 hits

Related Sentences

# PMID Sentence
1 15695367 Although the N-terminal RD binds transducin beta-like protein 1 (TBL1), TBLR1, and mSin3, deletion of this region did not affect the ability of N-CoR to mediate repression by TR.
2 15695367 By contrast, deletion of the deacetylase activating domain (DAD) that binds and activates histone deacetylase 3 dramatically hampered N-CoR's function as a TR corepressor.
3 18704835 In the mare, there is little, if any, P4 in the maternal plasma during late gestation and both progestagens and oestrogens are produced by a feto-placental unit which uses precursors supplied by the fetus to synthesise a range of C21 and C18 steroids, many of which are unique to the horse.
4 21459324 TBL1 deficiency resulted in inhibition of fatty acid oxidation due to impaired functional cooperation with its heterodimerization partner TBL-related (TBLR) 1 and the nuclear receptor peroxisome proliferator-activated receptor (PPAR) α.
5 21459324 As TBL1 expression levels were found to also inversely correlate with liver fat content in human patients, the lack of hepatic TBL1/TBLR1 cofactor activity may represent a molecular rationale for hepatic steatosis in subjects with obesity and the metabolic syndrome.