Ignet

Gene Information

Gene symbol: TBPL1

Gene name: TBP-like 1

HGNC ID: 11589

Synonyms: TLP, STUD, TRF2, TLF

Related Genes

#	Gene Symbol	Number of hits
1	C11orf6	1 hits
2	CD8A	1 hits
3	CREBBP	1 hits
4	EP300	1 hits
5	ETS1	1 hits
6	FLII	1 hits
7	SERPINA7	1 hits
8	SERPINH1	1 hits
9	TAF1	1 hits
10	TBP	1 hits
11	TTR	1 hits

Related Sentences

#	PMID	Sentence
1	7578887	The percentage of CD4+PBL was higher in NOD/Smrf females than males, was intermediate in [NOD X NON] F1 mice and approximated a 1:1 distribution in F1 mice backcrossed to either NOD or NON parental strains, suggesting primary control of the phenotype by an incompletely dominant gene, but not excluding additional effects by other genes.
2	7578887	We term this primary gene Tlf(T lymphocyte frequency) because it also influenced the percentage of CD8+ T cells, although to lesser extent and independently from the MHC previously shown to lower the CD8+ T cell fraction in NON mice.
3	7578887	Dihydrotestosterone simultaneously lowered CD4+ PBL levels and prevented diabetes in NOD females while, in vitro, it had a differential effect on Con A elicited cytokines, increasing IL-2 22% and decreasing IL-4 39% (p < 0.0001).
4	9001194	TLF (d < 1.210 kg/L) shown to be free of plasma T4 transport proteins (TBG, TTR, HSA) was equilibrated with 0.3 nM 125I-labeled T4, T3 or reverse T3 (rT3) and chromatographed on Sepharose CL-6B.
5	9754812	Candidate genes for Tlf are Ets1 and Fli1, proximally and Igif distally.
6	14726532	The general transcription factor TFIID sets the mRNA start site and consists of TATA-binding protein and associated factors (TAF(II)s), some of which are also present in SPT-ADA-GCN5 (SAGA)-related complexes.
7	14726532	In yeast, results of multiple studies indicate that TFIID-specific TAF(II)s are not required for the transcription of most genes, implying that intact TFIID may have a surprisingly specialized role in transcription.
8	14726532	Previously, we investigated functions of four shared TFIID/SAGA TAF(II)s in Caenorhabditis elegans.
9	14726532	Whereas TAF-4 was required for essentially all embryonic transcription, TAF-5, TAF-9, and TAF-10 were dispensable at multiple developmental and other metazoan-specific promoters.
10	14726532	Here we show evidence that in C. elegans embryos transcription of most genes requires TFIID-specific TAF-1.
11	14726532	TAF-2, which binds core promoters with TAF-1, appears to be required for a similarly substantial proportion of transcription.
12	14726532	C. elegans TAF-1 overlaps functionally with the coactivator p300/CBP (CBP-1), and at some genes it is required along with the TBP-like protein TLF(TRF2).
13	14726532	We conclude that during C. elegans embryogenesis TAF-1 and TFIID have broad roles in transcription and development and that TFIID and TLF may act together at certain promoters.
14	14726532	The general transcription factor TFIID sets the mRNA start site and consists of TATA-binding protein and associated factors (TAF(II)s), some of which are also present in SPT-ADA-GCN5 (SAGA)-related complexes.
15	14726532	In yeast, results of multiple studies indicate that TFIID-specific TAF(II)s are not required for the transcription of most genes, implying that intact TFIID may have a surprisingly specialized role in transcription.
16	14726532	Previously, we investigated functions of four shared TFIID/SAGA TAF(II)s in Caenorhabditis elegans.
17	14726532	Whereas TAF-4 was required for essentially all embryonic transcription, TAF-5, TAF-9, and TAF-10 were dispensable at multiple developmental and other metazoan-specific promoters.
18	14726532	Here we show evidence that in C. elegans embryos transcription of most genes requires TFIID-specific TAF-1.
19	14726532	TAF-2, which binds core promoters with TAF-1, appears to be required for a similarly substantial proportion of transcription.
20	14726532	C. elegans TAF-1 overlaps functionally with the coactivator p300/CBP (CBP-1), and at some genes it is required along with the TBP-like protein TLF(TRF2).
21	14726532	We conclude that during C. elegans embryogenesis TAF-1 and TFIID have broad roles in transcription and development and that TFIID and TLF may act together at certain promoters.