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PMID |
Sentence |
1 |
22791750
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We replicated SNPs in or near SC4MOL and TCERG1L in West Africans.
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2 |
22791750
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The meta-analysis of 1497 African Americans and West Africans yielded genome-wide significant associations for SNPs in the SC4MOL gene: rs17046216 (P = 1.7 × 10(-8) and 2.9 × 10(-8) for FI and IR, respectively); and near the TCERG1L gene with rs7077836 as the top scoring (P = 7.5 × 10(-9) and 4.9 × 10(-10) for FI and IR, respectively).
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3 |
22791750
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In addition, we replicated previous GWAS findings for IR and FI in Europeans for GCKR, and for variants in four T2D loci (FTO, IRS1, KLF14 and PPARG) which exert their action via IR.
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4 |
22791750
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In summary, variants in/near SC4MOL, and TCERG1L were associated with FI and IR in this cohort of African Americans and were replicated in West Africans.
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5 |
22791750
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TCERG1L is associated with plasma adiponectin, a key modulator of obesity, inflammation, IR and diabetes.
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6 |
22791750
|
We replicated SNPs in or near SC4MOL and TCERG1L in West Africans.
|
7 |
22791750
|
The meta-analysis of 1497 African Americans and West Africans yielded genome-wide significant associations for SNPs in the SC4MOL gene: rs17046216 (P = 1.7 × 10(-8) and 2.9 × 10(-8) for FI and IR, respectively); and near the TCERG1L gene with rs7077836 as the top scoring (P = 7.5 × 10(-9) and 4.9 × 10(-10) for FI and IR, respectively).
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8 |
22791750
|
In addition, we replicated previous GWAS findings for IR and FI in Europeans for GCKR, and for variants in four T2D loci (FTO, IRS1, KLF14 and PPARG) which exert their action via IR.
|
9 |
22791750
|
In summary, variants in/near SC4MOL, and TCERG1L were associated with FI and IR in this cohort of African Americans and were replicated in West Africans.
|
10 |
22791750
|
TCERG1L is associated with plasma adiponectin, a key modulator of obesity, inflammation, IR and diabetes.
|
11 |
22791750
|
We replicated SNPs in or near SC4MOL and TCERG1L in West Africans.
|
12 |
22791750
|
The meta-analysis of 1497 African Americans and West Africans yielded genome-wide significant associations for SNPs in the SC4MOL gene: rs17046216 (P = 1.7 × 10(-8) and 2.9 × 10(-8) for FI and IR, respectively); and near the TCERG1L gene with rs7077836 as the top scoring (P = 7.5 × 10(-9) and 4.9 × 10(-10) for FI and IR, respectively).
|
13 |
22791750
|
In addition, we replicated previous GWAS findings for IR and FI in Europeans for GCKR, and for variants in four T2D loci (FTO, IRS1, KLF14 and PPARG) which exert their action via IR.
|
14 |
22791750
|
In summary, variants in/near SC4MOL, and TCERG1L were associated with FI and IR in this cohort of African Americans and were replicated in West Africans.
|
15 |
22791750
|
TCERG1L is associated with plasma adiponectin, a key modulator of obesity, inflammation, IR and diabetes.
|
16 |
22791750
|
We replicated SNPs in or near SC4MOL and TCERG1L in West Africans.
|
17 |
22791750
|
The meta-analysis of 1497 African Americans and West Africans yielded genome-wide significant associations for SNPs in the SC4MOL gene: rs17046216 (P = 1.7 × 10(-8) and 2.9 × 10(-8) for FI and IR, respectively); and near the TCERG1L gene with rs7077836 as the top scoring (P = 7.5 × 10(-9) and 4.9 × 10(-10) for FI and IR, respectively).
|
18 |
22791750
|
In addition, we replicated previous GWAS findings for IR and FI in Europeans for GCKR, and for variants in four T2D loci (FTO, IRS1, KLF14 and PPARG) which exert their action via IR.
|
19 |
22791750
|
In summary, variants in/near SC4MOL, and TCERG1L were associated with FI and IR in this cohort of African Americans and were replicated in West Africans.
|
20 |
22791750
|
TCERG1L is associated with plasma adiponectin, a key modulator of obesity, inflammation, IR and diabetes.
|