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Gene Information
Gene symbol: TCF12
Gene name: transcription factor 12
HGNC ID: 11623
Synonyms: HEB, HTF4, HsT17266, bHLHb20
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
11914736
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The majority of the islet-restricted (BETA2, PDX-1, RIP3b1-Act/C1) and ubiquitous (E2A, HEB) insulin-binding proteins have been characterized.
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2 |
11914736
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Their DNA binding activity and their transactivating potency can be modified in response to nutrients (glucose, NEFA) or hormonal stimuli (insulin, leptin, glucagon like peptide-1, growth hormone, prolactin) through kinase-dependent signalling pathways (PI3-K, p38MAPK, PKA, CaMK) modulating their affinities for DNA and/or for each other.
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