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Gene Information
Gene symbol: TCF7L1
Gene name: transcription factor 7-like 1 (T-cell specific, HMG-box)
HGNC ID: 11640
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CTNNB1 | 1 hits |
| 2 | DVL2 | 1 hits |
| 3 | HNF4A | 1 hits |
| 4 | INS | 1 hits |
| 5 | JUP | 1 hits |
| 6 | MYC | 1 hits |
| 7 | TCF7 | 1 hits |
| 8 | TCF7L2 | 1 hits |
| 9 | WNT10A | 1 hits |
| 10 | WNT2B | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19165345 | Multiple members of the Wnt signaling pathway, including TCF7L2, Wnt2b, beta-catenin, pGSK3beta, TCF3, cyclinD1, and c-myc, were undetectable or expressed at low levels in islets from nondiabetic individuals, but were also upregulated specifically in islets of type II diabetic patients. |
| 2 | 20675304 | Insulin treatment and high-fat diet feeding reduces the expression of three Tcf genes in rodent pancreas. |
| 3 | 20675304 | Both Tcf7 and Tcf7l1, but not Lef1, were expressed in the pancreas. |
| 4 | 20675304 | The expression of the three Tcf genes (Tcf7, Tcf7l1, and Tcf7l2) in the pancreas was reduced by treatment with insulin or high-fat diet feeding, in contrast to the stimulation of Tcf7l2 expression by insulin in the gut. |
| 5 | 20675304 | Insulin treatment and high-fat diet feeding reduces the expression of three Tcf genes in rodent pancreas. |
| 6 | 20675304 | Both Tcf7 and Tcf7l1, but not Lef1, were expressed in the pancreas. |
| 7 | 20675304 | The expression of the three Tcf genes (Tcf7, Tcf7l1, and Tcf7l2) in the pancreas was reduced by treatment with insulin or high-fat diet feeding, in contrast to the stimulation of Tcf7l2 expression by insulin in the gut. |
| 8 | 22611086 | Promoters of these genes (Wnt10a, β-catenin, Dishevelled2, TCF3) displayed Bmal1 occupancy, indicating direct circadian regulation by Bmal1. |