Ignet

Gene Information

Gene symbol: TNFSF8

Gene name: tumor necrosis factor (ligand) superfamily, member 8

HGNC ID: 11938

Synonyms: CD153

Related Genes

#	Gene Symbol	Number of hits
1	CD4	1 hits
2	CD8A	1 hits
3	TNF	1 hits
4	TNFRSF8	1 hits

Related Sentences

#	PMID	Sentence
1	11960307	Association study between CD30 and CD30 ligand genes and type 1 diabetes in the Japanese population.
2	11960307	The purpose of this study was to determine whether CD30 or CD30L genes serve as a novel susceptibility gene for type 1 diabetes in humans.
3	11960307	We screened CD30 and CD30L genes for polymorphisms in Japanese patients with type 1 diabetes and control subjects.
4	11960307	Direct-sequencing analysis of the CD30 and CD30L genes revealed four polymorphisms: one in the CD30 gene (-201G/A from the transcription start site), and three in the CD30L gene [CA repeat in the promoter, 276G/A in the exon 3, -73T/C in the intron 3 (IVS3 -73T/C)].
5	11960307	Association studies revealed no association between the CD30 and CD30L genes and type 1 diabetes in the whole population.
6	11960307	In conclusion, we could not find significant association between CD30 or CD30L genes and type 1 diabetes, but (CA)(9) allele in the promotor or T allele of -73T/C in intron 3 in CD30L gene might play a minor role in the pathogenesis of type 1 diabetes, only in the Japanese female population.
7	11960307	Association study between CD30 and CD30 ligand genes and type 1 diabetes in the Japanese population.
8	11960307	The purpose of this study was to determine whether CD30 or CD30L genes serve as a novel susceptibility gene for type 1 diabetes in humans.
9	11960307	We screened CD30 and CD30L genes for polymorphisms in Japanese patients with type 1 diabetes and control subjects.
10	11960307	Direct-sequencing analysis of the CD30 and CD30L genes revealed four polymorphisms: one in the CD30 gene (-201G/A from the transcription start site), and three in the CD30L gene [CA repeat in the promoter, 276G/A in the exon 3, -73T/C in the intron 3 (IVS3 -73T/C)].
11	11960307	Association studies revealed no association between the CD30 and CD30L genes and type 1 diabetes in the whole population.
12	11960307	In conclusion, we could not find significant association between CD30 or CD30L genes and type 1 diabetes, but (CA)(9) allele in the promotor or T allele of -73T/C in intron 3 in CD30L gene might play a minor role in the pathogenesis of type 1 diabetes, only in the Japanese female population.
13	11960307	Association study between CD30 and CD30 ligand genes and type 1 diabetes in the Japanese population.
14	11960307	The purpose of this study was to determine whether CD30 or CD30L genes serve as a novel susceptibility gene for type 1 diabetes in humans.
15	11960307	We screened CD30 and CD30L genes for polymorphisms in Japanese patients with type 1 diabetes and control subjects.
16	11960307	Direct-sequencing analysis of the CD30 and CD30L genes revealed four polymorphisms: one in the CD30 gene (-201G/A from the transcription start site), and three in the CD30L gene [CA repeat in the promoter, 276G/A in the exon 3, -73T/C in the intron 3 (IVS3 -73T/C)].
17	11960307	Association studies revealed no association between the CD30 and CD30L genes and type 1 diabetes in the whole population.
18	11960307	In conclusion, we could not find significant association between CD30 or CD30L genes and type 1 diabetes, but (CA)(9) allele in the promotor or T allele of -73T/C in intron 3 in CD30L gene might play a minor role in the pathogenesis of type 1 diabetes, only in the Japanese female population.
19	11960307	Association study between CD30 and CD30 ligand genes and type 1 diabetes in the Japanese population.
20	11960307	The purpose of this study was to determine whether CD30 or CD30L genes serve as a novel susceptibility gene for type 1 diabetes in humans.
21	11960307	We screened CD30 and CD30L genes for polymorphisms in Japanese patients with type 1 diabetes and control subjects.
22	11960307	Direct-sequencing analysis of the CD30 and CD30L genes revealed four polymorphisms: one in the CD30 gene (-201G/A from the transcription start site), and three in the CD30L gene [CA repeat in the promoter, 276G/A in the exon 3, -73T/C in the intron 3 (IVS3 -73T/C)].
23	11960307	Association studies revealed no association between the CD30 and CD30L genes and type 1 diabetes in the whole population.
24	11960307	In conclusion, we could not find significant association between CD30 or CD30L genes and type 1 diabetes, but (CA)(9) allele in the promotor or T allele of -73T/C in intron 3 in CD30L gene might play a minor role in the pathogenesis of type 1 diabetes, only in the Japanese female population.
25	11960307	Association study between CD30 and CD30 ligand genes and type 1 diabetes in the Japanese population.
26	11960307	The purpose of this study was to determine whether CD30 or CD30L genes serve as a novel susceptibility gene for type 1 diabetes in humans.
27	11960307	We screened CD30 and CD30L genes for polymorphisms in Japanese patients with type 1 diabetes and control subjects.
28	11960307	Direct-sequencing analysis of the CD30 and CD30L genes revealed four polymorphisms: one in the CD30 gene (-201G/A from the transcription start site), and three in the CD30L gene [CA repeat in the promoter, 276G/A in the exon 3, -73T/C in the intron 3 (IVS3 -73T/C)].
29	11960307	Association studies revealed no association between the CD30 and CD30L genes and type 1 diabetes in the whole population.
30	11960307	In conclusion, we could not find significant association between CD30 or CD30L genes and type 1 diabetes, but (CA)(9) allele in the promotor or T allele of -73T/C in intron 3 in CD30L gene might play a minor role in the pathogenesis of type 1 diabetes, only in the Japanese female population.
31	11960307	Association study between CD30 and CD30 ligand genes and type 1 diabetes in the Japanese population.
32	11960307	The purpose of this study was to determine whether CD30 or CD30L genes serve as a novel susceptibility gene for type 1 diabetes in humans.
33	11960307	We screened CD30 and CD30L genes for polymorphisms in Japanese patients with type 1 diabetes and control subjects.
34	11960307	Direct-sequencing analysis of the CD30 and CD30L genes revealed four polymorphisms: one in the CD30 gene (-201G/A from the transcription start site), and three in the CD30L gene [CA repeat in the promoter, 276G/A in the exon 3, -73T/C in the intron 3 (IVS3 -73T/C)].
35	11960307	Association studies revealed no association between the CD30 and CD30L genes and type 1 diabetes in the whole population.
36	11960307	In conclusion, we could not find significant association between CD30 or CD30L genes and type 1 diabetes, but (CA)(9) allele in the promotor or T allele of -73T/C in intron 3 in CD30L gene might play a minor role in the pathogenesis of type 1 diabetes, only in the Japanese female population.
37	12930356	Critical roles of CD30/CD30L interactions in murine autoimmune diabetes.
38	12930356	CD30/CD30L is a member of tumour necrosis factor (TNF) receptor/TNF superfamily and has been implicated in immune-regulation.
39	12930356	In this study, we investigated the involvement of CD30/CD30L in the development of diabetes in NOD mice.
40	12930356	Flow cytometric analysis showed that CD30 and CD30L were highly expressed on CD4+ or CD8+ T cells in the spleen and pancreatic lymph node of younger NOD mice.
41	12930356	In addition, islet-specific CD4+ or CD8+ T cell lines expressed CD30 and CD30L.
42	12930356	In addition, the treatment with anti-CD30L mAb also inhibited the development of diabetes induced by adoptive transfer of spleen cells from diabetic NOD mice or islet-specific CD4+ or CD8+ T cell lines into NOD-SCID mice.
43	12930356	These results suggested that CD30/CD30L interaction plays important roles in both induction and effector phases of autoimmune diabetes in NOD mice.
44	12930356	Critical roles of CD30/CD30L interactions in murine autoimmune diabetes.
45	12930356	CD30/CD30L is a member of tumour necrosis factor (TNF) receptor/TNF superfamily and has been implicated in immune-regulation.
46	12930356	In this study, we investigated the involvement of CD30/CD30L in the development of diabetes in NOD mice.
47	12930356	Flow cytometric analysis showed that CD30 and CD30L were highly expressed on CD4+ or CD8+ T cells in the spleen and pancreatic lymph node of younger NOD mice.
48	12930356	In addition, islet-specific CD4+ or CD8+ T cell lines expressed CD30 and CD30L.
49	12930356	In addition, the treatment with anti-CD30L mAb also inhibited the development of diabetes induced by adoptive transfer of spleen cells from diabetic NOD mice or islet-specific CD4+ or CD8+ T cell lines into NOD-SCID mice.
50	12930356	These results suggested that CD30/CD30L interaction plays important roles in both induction and effector phases of autoimmune diabetes in NOD mice.
51	12930356	Critical roles of CD30/CD30L interactions in murine autoimmune diabetes.
52	12930356	CD30/CD30L is a member of tumour necrosis factor (TNF) receptor/TNF superfamily and has been implicated in immune-regulation.
53	12930356	In this study, we investigated the involvement of CD30/CD30L in the development of diabetes in NOD mice.
54	12930356	Flow cytometric analysis showed that CD30 and CD30L were highly expressed on CD4+ or CD8+ T cells in the spleen and pancreatic lymph node of younger NOD mice.
55	12930356	In addition, islet-specific CD4+ or CD8+ T cell lines expressed CD30 and CD30L.
56	12930356	In addition, the treatment with anti-CD30L mAb also inhibited the development of diabetes induced by adoptive transfer of spleen cells from diabetic NOD mice or islet-specific CD4+ or CD8+ T cell lines into NOD-SCID mice.
57	12930356	These results suggested that CD30/CD30L interaction plays important roles in both induction and effector phases of autoimmune diabetes in NOD mice.
58	12930356	Critical roles of CD30/CD30L interactions in murine autoimmune diabetes.
59	12930356	CD30/CD30L is a member of tumour necrosis factor (TNF) receptor/TNF superfamily and has been implicated in immune-regulation.
60	12930356	In this study, we investigated the involvement of CD30/CD30L in the development of diabetes in NOD mice.
61	12930356	Flow cytometric analysis showed that CD30 and CD30L were highly expressed on CD4+ or CD8+ T cells in the spleen and pancreatic lymph node of younger NOD mice.
62	12930356	In addition, islet-specific CD4+ or CD8+ T cell lines expressed CD30 and CD30L.
63	12930356	In addition, the treatment with anti-CD30L mAb also inhibited the development of diabetes induced by adoptive transfer of spleen cells from diabetic NOD mice or islet-specific CD4+ or CD8+ T cell lines into NOD-SCID mice.
64	12930356	These results suggested that CD30/CD30L interaction plays important roles in both induction and effector phases of autoimmune diabetes in NOD mice.
65	12930356	Critical roles of CD30/CD30L interactions in murine autoimmune diabetes.
66	12930356	CD30/CD30L is a member of tumour necrosis factor (TNF) receptor/TNF superfamily and has been implicated in immune-regulation.
67	12930356	In this study, we investigated the involvement of CD30/CD30L in the development of diabetes in NOD mice.
68	12930356	Flow cytometric analysis showed that CD30 and CD30L were highly expressed on CD4+ or CD8+ T cells in the spleen and pancreatic lymph node of younger NOD mice.
69	12930356	In addition, islet-specific CD4+ or CD8+ T cell lines expressed CD30 and CD30L.
70	12930356	In addition, the treatment with anti-CD30L mAb also inhibited the development of diabetes induced by adoptive transfer of spleen cells from diabetic NOD mice or islet-specific CD4+ or CD8+ T cell lines into NOD-SCID mice.
71	12930356	These results suggested that CD30/CD30L interaction plays important roles in both induction and effector phases of autoimmune diabetes in NOD mice.
72	12930356	Critical roles of CD30/CD30L interactions in murine autoimmune diabetes.
73	12930356	CD30/CD30L is a member of tumour necrosis factor (TNF) receptor/TNF superfamily and has been implicated in immune-regulation.
74	12930356	In this study, we investigated the involvement of CD30/CD30L in the development of diabetes in NOD mice.
75	12930356	Flow cytometric analysis showed that CD30 and CD30L were highly expressed on CD4+ or CD8+ T cells in the spleen and pancreatic lymph node of younger NOD mice.
76	12930356	In addition, islet-specific CD4+ or CD8+ T cell lines expressed CD30 and CD30L.
77	12930356	In addition, the treatment with anti-CD30L mAb also inhibited the development of diabetes induced by adoptive transfer of spleen cells from diabetic NOD mice or islet-specific CD4+ or CD8+ T cell lines into NOD-SCID mice.
78	12930356	These results suggested that CD30/CD30L interaction plays important roles in both induction and effector phases of autoimmune diabetes in NOD mice.