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Gene Information
Gene symbol: TOLLIP
Gene name: toll interacting protein
HGNC ID: 16476
Synonyms: IL-1RAcPIP
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ATF2 | 1 hits |
| 2 | HOXA3 | 1 hits |
| 3 | IL1RL1 | 1 hits |
| 4 | IRAK3 | 1 hits |
| 5 | MYD88 | 1 hits |
| 6 | SIGIRR | 1 hits |
| 7 | SOCS1 | 1 hits |
| 8 | TNFAIP3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19544454 | Microarray analyses of HOXA3-treated wounds revealed that indeed HOXA3 locally increased expression of genes that selectively promote stem/progenitor cell mobilization and recruitment while also suppressing expression of numerous members of the proinflammatory nuclear factor kappaB pathway, including myeloid differentiation primary response gene 88 and toll-interacting protein. |
| 2 | 22706082 | Unlike high-dose LPS, low-dose LPS does not induce robust activation of NF-κB, MAPKs, PI3K, or anti-inflammatory mediators. |
| 3 | 22706082 | Instead, low-dose LPS induces activating transcription factor 2 through Toll-interacting protein-mediated generation of mitochondrial reactive oxygen species, allowing mild induction of proinflammatory mediators. |
| 4 | 23149823 | These were accompanied by overexpression of negative regulators of NFκB, TLR, and other proinflammatory pathways, e.g., A20, SOCS1, IRAK-M, IκBα, Triad3A, Tollip, SIGIRR, and ST2L. |
| 5 | 23149823 | Anti-inflammatory and immunomodulatory molecules, e.g., IL-10, IL-4, and TSLP that favor TH2 responses were strongly induced. |