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Gene Information
Gene symbol: TP53BP1
Gene name: tumor protein p53 binding protein 1
HGNC ID: 11999
Synonyms: 53BP1, p202
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ASH2L | 1 hits |
| 2 | C16orf53 | 1 hits |
| 3 | DPY30 | 1 hits |
| 4 | MLL2 | 1 hits |
| 5 | MLL3 | 1 hits |
| 6 | NCOA6 | 1 hits |
| 7 | PAXIP1 | 1 hits |
| 8 | RBBP5 | 1 hits |
| 9 | WDR5 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17500065 | PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex. |
| 2 | 17500065 | Here we show that while ectopically expressed PTIP is capable of interacting with DNA damage response proteins including 53BP1, endogenous PTIP, and a novel protein PA1 are both components of a Set1-like histone methyltransferase (HMT) complex that also contains ASH2L, RBBP5, WDR5, hDPY-30, NCOA6, SET domain-containing HMTs MLL3 and MLL4, and substoichiometric amount of JmjC domain-containing putative histone demethylase UTX. |
| 3 | 17500065 | Furthermore, PA1 binds PTIP directly and requires PTIP for interaction with the rest of the complex. |
| 4 | 17500065 | The evolutionarily conserved hDPY-30, ASH2L, RBBP5, and WDR5 likely constitute a subcomplex that is shared by all human Set1-like HMT complexes. |
| 5 | 17500065 | In contrast, PTIP, PA1, and UTX specifically associate with the PTIP complex. |