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Gene Information

Gene symbol: TRD

Gene name: T cell receptor delta locus

HGNC ID: 12252

Related Genes

# Gene Symbol Number of hits
1 CXCL10 1 hits
2 TRB 1 hits
3 TRG 1 hits

Related Sentences

# PMID Sentence
1 18708940 Subcutaneous panniculitis-like T-cell lymphoma (SPTL) is defined as a rare cytotoxic alpha/beta T-cell lymphoma characterized by primary involvement of subcutaneous tissue mimicking panniculitis and a predominant CD3+/CD4-/CD8+ phenotype in 2005 World Health Organization-European Organization for Research and Treatment of Cancer (WHO-EORTC) classification for cutaneous lymphomas.
2 18708940 Besides the common features described before, unusual CD4+/CD8- and CD4-/CD8- T-cell phenotypes were noted in 2 of our cases, respectively.
3 18708940 The frequency of rearranged TCRB, TCRG, and TCRD genes detected by BIOMED-2 multiplex polymerase chain reaction tubes was 80%, 67%, and 13%, respectively, with a total clonality detection rate of 100%.
4 18708940 We conclude that SPTL as a cytotoxic lymphoma derived from alpha/beta T cell has a predominant CD4-/CD8+ phenotype, but unusual CD4+/CD8- and CD4-/CD8- phenotypes do exist.
5 23352833 Autocrine CCL2, CXCL4, CXCL9 and CXCL10 signal in retinal endothelial cells and are enhanced in diabetic retinopathy.
6 23352833 This study aimed at examining the presence and role of chemokines (angiogenic CCL2/MCP-1 and angiostatic CXCL4/PF-4, CXCL9/Mig, CXCL10/IP-10) in proliferative diabetic retinopathy (PDR).
7 23352833 MCP-1, PF-4, Mig, IP-10 and VEGF levels in vitreous fluid from PDR patients were significantly higher than in controls.
8 23352833 Exploratory regression analysis identified associations between higher levels of IP-10 and inactive PDR and PDR with TRD.
9 23352833 VEGF levels correlated positively with MCP-1 and IP-10.
10 23352833 Significant positive correlations were observed between MCP-1 and IP-10 levels.
11 23352833 HRMEC produced MCP-1, Mig and IP-10 after stimulation with IFN-γ, IL-1β or lipopolysaccharide.
12 23352833 IFN-γ synergistically enhanced Mig and IP-10 production in response to IL-1β or lipopolysaccharide.
13 23352833 MCP-1 was produced by HRMEC in response to VEGF treatment and activated HRMEC via the ERK and Akt/PKB pathway.
14 23352833 On the other hand, phosphorylation of ERK induced by VEGF and MCP-1 was inhibited by PF-4, Mig and IP-10.