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Gene Information

Gene symbol: TRDN

Gene name: triadin

HGNC ID: 12261

Related Genes

# Gene Symbol Number of hits
1 APOE 1 hits
2 SDC2 1 hits

Related Sentences

# PMID Sentence
1 14674716 Co-inheritance of specific genotypes of HSPG and ApoE gene increases risk of type 2 diabetic nephropathy.
2 14674716 The objective of this paper is to investigate co-inheritance of specific HSPG and ApoE genotypes in the development of Chinese type 2 diabetic nephropathy.
3 14674716 PCR-RFLP was used to detect HSPG and ApoE genotypes in 385 Chinese subjects including 298 patients with type 2 diabetes mellitus (T2DM) and 87 non-diabetic controls (Non-DM).
4 14674716 We then compared the relative frequencies of various HSPG and ApoE genotypes and alleles among the groups, searching for predictive trends.
5 14674716 Genotype analysis showed that the TT or TG of HSPG gene were paired with the E2/2 or E2/3 of ApoE gene significantly more frequently in the TDN group than in the Non-DN group, with an odds ratio of 3.03 (95% CI 1.03-8.90).
6 14674716 There was no significant differences in other combinations of genotypes in HSPG and ApoE genes between TDN and Non-DN group.
7 14674716 These results suggest that the HSPG T allele is a risk factor for the development of severe diabetic nephropathy in type 2 diabetic patients, and that the ApoE E2 allele is a risk factor for the occurrence of type 2 diabetes mellitus in Chinese general population.
8 14674716 Co-inheritance of specific genotypes of HSPG and ApoE gene increases risk of type 2 diabetic nephropathy.
9 14674716 The objective of this paper is to investigate co-inheritance of specific HSPG and ApoE genotypes in the development of Chinese type 2 diabetic nephropathy.
10 14674716 PCR-RFLP was used to detect HSPG and ApoE genotypes in 385 Chinese subjects including 298 patients with type 2 diabetes mellitus (T2DM) and 87 non-diabetic controls (Non-DM).
11 14674716 We then compared the relative frequencies of various HSPG and ApoE genotypes and alleles among the groups, searching for predictive trends.
12 14674716 Genotype analysis showed that the TT or TG of HSPG gene were paired with the E2/2 or E2/3 of ApoE gene significantly more frequently in the TDN group than in the Non-DN group, with an odds ratio of 3.03 (95% CI 1.03-8.90).
13 14674716 There was no significant differences in other combinations of genotypes in HSPG and ApoE genes between TDN and Non-DN group.
14 14674716 These results suggest that the HSPG T allele is a risk factor for the development of severe diabetic nephropathy in type 2 diabetic patients, and that the ApoE E2 allele is a risk factor for the occurrence of type 2 diabetes mellitus in Chinese general population.