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Gene Information
Gene symbol: TRIM21
Gene name: tripartite motif containing 21
HGNC ID: 11312
Synonyms: RNF81, RO52
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | HSPA1A | 1 hits |
| 2 | TROVE2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9767451 | The role of polyclonal B-cell activation was examined by measuring total gamma-globulin as well as IgG reactive with other nuclear antigens including Ro60, Ro52 and La, which although not a major component of the autoantibody responses in these mice, did show small but significant increases following immunization with M. bovis. |
| 2 | 11014806 | While [PSI(+)] stability is normal in strains lacking SSA1, SSA2, or both, SSA1-21 strains with a deletion of SSA2 cannot propagate [PSI(+)]. |
| 3 | 15082786 | Earlier characterization of HSP70 (SSA1) mutations suggested that [PSI(+)] propagation is impaired by alterations that enhance Ssa1p's substrate binding. |
| 4 | 15082786 | We also find that the GPTVEEVD motif is important for physical interaction with Hsp40 (Ydj1p), another Hsp70 cochaperone that promotes substrate binding but is dispensable for viability. |
| 5 | 15082786 | We further find that depleting Cpr7p, an Hsp90 TPR cochaperone and CyP-40 cyclophilin homolog, improved [PSI(+)] propagation in SSA1 mutants. |