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Gene Information
Gene symbol: TRPC1
Gene name: transient receptor potential cation channel, subfamily C, member 1
HGNC ID: 12333
Synonyms: HTRP-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | TRPC3 | 1 hits |
| 2 | TRPC6 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17699555 | In cultured human MCs, high glucose significantly reduced expression of TRPC6 protein, but there was no effect on either TRPC1 or TRPC3. |
| 2 | 17699555 | In glomeruli isolated from streptozotocin-induced diabetic rats, TRPC6, but not TRPC1, was markedly reduced compared with the glomeruli of control rats. |
| 3 | 17699555 | Patch-clamp experiments showed that ANG II-stimulated membrane currents in MCs were significantly attenuated or enhanced by knockdown or overexpression of TRPC6, respectively. |
| 4 | 17699555 | Fura-2 fluorescence measurements revealed that the ANG II-induced Ca(2+) influxes were markedly inhibited in MCs with TRPC6 knockdown, reminiscent of the impaired Ca(2+) entry in response to ANG II in high glucose-treated MCs. |
| 5 | 17699555 | In cultured human MCs, high glucose significantly reduced expression of TRPC6 protein, but there was no effect on either TRPC1 or TRPC3. |
| 6 | 17699555 | In glomeruli isolated from streptozotocin-induced diabetic rats, TRPC6, but not TRPC1, was markedly reduced compared with the glomeruli of control rats. |
| 7 | 17699555 | Patch-clamp experiments showed that ANG II-stimulated membrane currents in MCs were significantly attenuated or enhanced by knockdown or overexpression of TRPC6, respectively. |
| 8 | 17699555 | Fura-2 fluorescence measurements revealed that the ANG II-induced Ca(2+) influxes were markedly inhibited in MCs with TRPC6 knockdown, reminiscent of the impaired Ca(2+) entry in response to ANG II in high glucose-treated MCs. |
| 9 | 19393642 | However, the protein expression of TRPC1 and TRPC6 was downregulated in the diabetic group by 50%. |
| 10 | 20337661 | Expression of TRPC1, TRPC3 and TRPC6 mRNA and protein was found in Wistar rats. |
| 11 | 20337661 | The expression of TRPC1 and TRPC6, but not TRPC3, was increased approximately twofold in GK rats compared with Wistar rats. 5. |
| 12 | 20337661 | Expression of TRPC1, TRPC3 and TRPC6 mRNA and protein was found in Wistar rats. |
| 13 | 20337661 | The expression of TRPC1 and TRPC6, but not TRPC3, was increased approximately twofold in GK rats compared with Wistar rats. 5. |