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Gene Information
Gene symbol: TRPV2
Gene name: transient receptor potential cation channel, subfamily V, member 2
HGNC ID: 18082
Synonyms: VRL, VRL-1, VRL1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CLU | 1 hits |
| 2 | IL6 | 1 hits |
| 3 | INS | 1 hits |
| 4 | NFKBIA | 1 hits |
| 5 | TNF | 1 hits |
| 6 | TRPM2 | 1 hits |
| 7 | TRPM4 | 1 hits |
| 8 | TRPM5 | 1 hits |
| 9 | TRPV1 | 1 hits |
| 10 | TRPV4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20599720 | Pharmacologic experiments suggested that TRPV family members, but neither TRPC nor TRPM family members, are involved in the LPS-induced TNFalpha and IL-6 production in RAW264 macrophages. |
| 2 | 20599720 | ShRNA against TRPV2 inhibited the LPS-induced TNFalpha and IL-6 production as well as IkappaBalpha degradation. |
| 3 | 20599720 | BAPTA/AM abolished LPS-induced TNFalpha and IL-6 production, while EGTA only partially suppressed LPS-induced IL-6 production, but not TNFalpha production. |
| 4 | 20599720 | In addition to Ca2+ mobilization through the IP3-receptor, TRPV2-mediated intracellular Ca2+ mobilization is involved in NFkappaB-dependent TNFalpha and IL-6 expression, while extracellular Ca2+ entry is involved in NFkappaB-independent IL-6 production. |
| 5 | 20599720 | Pharmacologic experiments suggested that TRPV family members, but neither TRPC nor TRPM family members, are involved in the LPS-induced TNFalpha and IL-6 production in RAW264 macrophages. |
| 6 | 20599720 | ShRNA against TRPV2 inhibited the LPS-induced TNFalpha and IL-6 production as well as IkappaBalpha degradation. |
| 7 | 20599720 | BAPTA/AM abolished LPS-induced TNFalpha and IL-6 production, while EGTA only partially suppressed LPS-induced IL-6 production, but not TNFalpha production. |
| 8 | 20599720 | In addition to Ca2+ mobilization through the IP3-receptor, TRPV2-mediated intracellular Ca2+ mobilization is involved in NFkappaB-dependent TNFalpha and IL-6 expression, while extracellular Ca2+ entry is involved in NFkappaB-independent IL-6 production. |
| 9 | 21785227 | Interestingly, six of them (TRPM2, TRPM4, TRPM5, TRPV1, TRPV2 and TRPV4) are thermosensitive TRP channels. |
| 10 | 21785227 | TRPM channels (TRPM2, TRPM4 and TRPM5) control insulin secretion levels by sensing intracellular Ca2+ increase, NAD metabolites, or hormone receptor activation. |
| 11 | 21785227 | TRPV2 is involved not only in insulin secretion but also cell proliferation, and is regulated by the autocrine effects of insulin. |
| 12 | 21785227 | Interestingly, six of them (TRPM2, TRPM4, TRPM5, TRPV1, TRPV2 and TRPV4) are thermosensitive TRP channels. |
| 13 | 21785227 | TRPM channels (TRPM2, TRPM4 and TRPM5) control insulin secretion levels by sensing intracellular Ca2+ increase, NAD metabolites, or hormone receptor activation. |
| 14 | 21785227 | TRPV2 is involved not only in insulin secretion but also cell proliferation, and is regulated by the autocrine effects of insulin. |