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Gene Information
Gene symbol: TRPV6
Gene name: transient receptor potential cation channel, subfamily V, member 6
HGNC ID: 14006
Synonyms: CaT1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BGLAP | 1 hits |
| 2 | CLDN2 | 1 hits |
| 3 | KL | 1 hits |
| 4 | S100A6 | 1 hits |
| 5 | SLC7A1 | 1 hits |
| 6 | SPP1 | 1 hits |
| 7 | TNFSF11 | 1 hits |
| 8 | TRPM6 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16557223 | Reverse transcriptase-polymerase chain reaction revealed significant increases in messenger RNA abundance of transient potential receptor (TRP) V5 (223 +/- 10%), TRPV6 (177 +/- 9%), calbindin-D28k (231 +/- 8%), and TRPM6 (165 +/- 8%) in diabetic rats. |
| 2 | 16557223 | Immunofluorescent studies of renal sections showed significant increase in calbindin-D28k (238 +/- 10%) and TRPV5 (211 +/- 10%), but no changes in paracellin-1 in Western blotting (cortex: 110 +/- 7%; medulla: 99 +/- 7%). |
| 3 | 19544385 | NVCMs infected with adenovirus expressing the L-arginine transporter, CAT1, and NVCMs supplemented with L-arginine both exhibited significant (all P < 0.05) improvements in NO generation and mitochondrial membrane potentials, with a concomitant significant fall in ROS production and lactate dehydrogenase release during hypoxia-reoxygenation. |
| 4 | 19544385 | These improved contractile responses were not dependent on coronary flow but were associated with a significant decrease in nitrotyrosine formation and increases in phosphorylation of both Akt and troponin I. |
| 5 | 19544385 | Increasing L-arginine availability via increased CAT1 expression or by supplementation improves myocardial responses to I-R. |
| 6 | 19544385 | NVCMs infected with adenovirus expressing the L-arginine transporter, CAT1, and NVCMs supplemented with L-arginine both exhibited significant (all P < 0.05) improvements in NO generation and mitochondrial membrane potentials, with a concomitant significant fall in ROS production and lactate dehydrogenase release during hypoxia-reoxygenation. |
| 7 | 19544385 | These improved contractile responses were not dependent on coronary flow but were associated with a significant decrease in nitrotyrosine formation and increases in phosphorylation of both Akt and troponin I. |
| 8 | 19544385 | Increasing L-arginine availability via increased CAT1 expression or by supplementation improves myocardial responses to I-R. |
| 9 | 22782502 | When occupied by 1,25D, VDR interacts with the retinoid X receptor (RXR) to form a heterodimer that binds to vitamin D responsive elements in the region of genes directly controlled by 1,25D. |
| 10 | 22782502 | For example, 1,25D induces RANKL, SPP1 (osteopontin), and BGP (osteocalcin) to govern bone mineral remodeling; TRPV6, CaBP(9k), and claudin 2 to promote intestinal calcium absorption; and TRPV5, klotho, and Npt2c to regulate renal calcium and phosphate reabsorption. |
| 11 | 22782502 | VDR appears to function unliganded by 1,25D in keratinocytes to drive mammalian hair cycling via regulation of genes such as CASP14, S100A8, SOSTDC1, and others affecting Wnt signaling. |