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Gene Information
Gene symbol: UBA52
Gene name: ubiquitin A-52 residue ribosomal protein fusion product 1
HGNC ID: 12458
Synonyms: RPL40, CEP52, HUBCEP52, MGC57125, MGC126879, MGC126881, L40
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GREM1 | 1 hits |
| 2 | HSD17B3 | 1 hits |
| 3 | MIOX | 1 hits |
| 4 | RAP1B | 1 hits |
| 5 | RPS27A | 1 hits |
| 6 | SPP1 | 1 hits |
| 7 | TIMM44 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11937760 | Recently, transforming growth factor beta driven secreted proteins, i.e., connective tissue growth factor and gremlin (bone morphogenetic protein 2), have been identified, and their expression has been correlated with the tissue changes seen in diabetic nephropathy in the adult population. |
| 2 | 11937760 | They included: (1) a translocase inner mitochondrial membrane 44 that is involved in the ATP-dependent import of preproteins from the cytosol into the mitochondrial matrix; (2) a kidney-specific aldo-keto reductase that utilizes NADPH and NADH as cofactors in the reduction of aromatic aldehydes and aldohexoses; (3) Rap1b, a Ras-related small GTP-binding protein that behaves as a GTPase and cycles between GTP-bound (active) and GDP-bound (inactive) states associated with conformational change, and (4) a fusion protein of ubiquitin polypeptide and ribosomal protein L40 (UbA(52) or ubiquitin/60) that is intimately involved in the ubiquitin-dependent proteasome pathway related to the accelerated degradation of proteins under various stress conditions, such as those seen in patients with cancer and diabetes mellitus. |
| 3 | 12171997 | Among them was UbA52, a ubiquitin ribosomal fusion protein. |
| 4 | 21252517 | Several genes, such as Tim44 (translocase of inner mitochondrial membrane- 44), RSOR/MIOX (renal specific oxidoreductase/myo-inositol oxygenase), UbA52, Rap1b (Ras-related GTPase), gremlin, osteopontin, hydroxysteroid dehydrogenase- 3β isotype 4 and those of the Wnt signaling pathway, were identified as differentially expressed genes in kidneys of diabetic rodents. |