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Gene Information
Gene symbol: VAMP4
Gene name: vesicle-associated membrane protein 4
HGNC ID: 12645
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | NAPA | 1 hits |
| 2 | NAPG | 1 hits |
| 3 | NSF | 1 hits |
| 4 | SNAP23 | 1 hits |
| 5 | SNAP25 | 1 hits |
| 6 | STX5 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17922004 | Here, we show that lipid droplets are associated with proteins involved in fusion processes in the cell: NSF (N-ethylmaleimide-sensitive-factor), alpha-SNAP (soluble NSF attachment protein) and the SNAREs (SNAP receptors), SNAP23 (synaptosomal-associated protein of 23 kDa), syntaxin-5 and VAMP4 (vesicle-associated membrane protein 4). |
| 2 | 17922004 | Knockdown of the genes for SNAP23, syntaxin-5 or VAMP4, or microinjection of a dominant-negative mutant of alpha-SNAP, decreases the rate of fusion and the size of the lipid droplets. |
| 3 | 17922004 | We also show that oleic acid treatment decreases the insulin sensitivity of heart muscle cells, and this sensitivity is completely restored by transfection with SNAP23. |
| 4 | 17922004 | Thus, SNAP23 might be a link between insulin sensitivity and the inflow of fatty acids to the cell. |
| 5 | 17922004 | Here, we show that lipid droplets are associated with proteins involved in fusion processes in the cell: NSF (N-ethylmaleimide-sensitive-factor), alpha-SNAP (soluble NSF attachment protein) and the SNAREs (SNAP receptors), SNAP23 (synaptosomal-associated protein of 23 kDa), syntaxin-5 and VAMP4 (vesicle-associated membrane protein 4). |
| 6 | 17922004 | Knockdown of the genes for SNAP23, syntaxin-5 or VAMP4, or microinjection of a dominant-negative mutant of alpha-SNAP, decreases the rate of fusion and the size of the lipid droplets. |
| 7 | 17922004 | We also show that oleic acid treatment decreases the insulin sensitivity of heart muscle cells, and this sensitivity is completely restored by transfection with SNAP23. |
| 8 | 17922004 | Thus, SNAP23 might be a link between insulin sensitivity and the inflow of fatty acids to the cell. |
| 9 | 21596547 | The fusion is catalyzed by the SNARE proteins SNAP23, syntaxin-5 and VAMP4. |
| 10 | 21596547 | SNAP23 is involved in the insulin dependent translocation of GLUT4 to the plasma membrane, and has an important role in the development of insulin resistance. |
| 11 | 21596547 | Thus fatty acids relocalize SNAP23 from the plasma membrane (and the translocation of GLUT 4) to the interior of the cell giving rise to insulin resistance. |
| 12 | 21596547 | Thus a missorting of SNAP23 is essential for the development of insulin resistance. |