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PMID |
Sentence |
1 |
19057892
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Vitreous levels of vasohibin-1 and vascular endothelial growth factor in patients with proliferative diabetic retinopathy.
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2 |
20659423
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Here, we analyzed how the expression of the two active anti-angiogenic VASH-1 isoforms p36 and p42 was altered during physiological and pathological muscle angio-adaptation.
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3 |
20659423
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Interestingly, expression patterns for p36 and p42 were different between plantaris and heart muscles.
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4 |
20659423
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Both p36 and p42 isoforms were increased, a signal in favor of some vessel destabilization and regression.
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5 |
20659423
|
In conclusion, our results bring evidence that endogenous VASH-1 isoforms p36 and p42 are key actors of physiological and pathological muscle angio-adaptation.
|
6 |
20659423
|
Here, we analyzed how the expression of the two active anti-angiogenic VASH-1 isoforms p36 and p42 was altered during physiological and pathological muscle angio-adaptation.
|
7 |
20659423
|
Interestingly, expression patterns for p36 and p42 were different between plantaris and heart muscles.
|
8 |
20659423
|
Both p36 and p42 isoforms were increased, a signal in favor of some vessel destabilization and regression.
|
9 |
20659423
|
In conclusion, our results bring evidence that endogenous VASH-1 isoforms p36 and p42 are key actors of physiological and pathological muscle angio-adaptation.
|
10 |
21228103
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An increase in the renal levels of VEGF-A, VEGFR-2, transforming growth factor (TGF)-β1, and monocyte chemoattractant protein-1 in diabetic animals was significantly suppressed by AdhVASH-1 (immunoblotting).
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11 |
21228103
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AdhVASH-1 treatment significantly recovered the loss and altered the distribution patterns of nephrin and zonula occludens (ZO)-1 and suppressed the increase in the number of fibroblast-specific protein-1 (FSP-1(+)) and desmin(+) podocytes in diabetic mice.
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12 |
21228103
|
In vitro, recombinant human VASH-1 (rhVASH-1) dose dependently suppressed the upregulation of VEGF induced by high ambient glucose (25 mM) in cultured mouse podocytes.
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13 |
21228103
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In addition, rhVASH-1 significantly recovered the mRNA levels of nephrin and the protein levels of ZO-1 and P-cadherin and suppressed the increase in protein levels of desmin, FSP-1, Snail, and Slug in podocytes under high-glucose condition.
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