Ignet
Search (e.g., vaccine, IFNG): Help
About
Home
Introduction
Statistics
Programs
Dignet
Gene
GenePair
BioSummarAI
Help & Docs
Documents
Help
FAQs
Links
Acknowledge
Disclaimer
Contact Us
UM Logo

UMMS Logo

UMMS Logo

Gene Information

Gene symbol: WWTR1

Gene name: WW domain containing transcription regulator 1

HGNC ID: 24042

Synonyms: TAZ, DKFZp586I1419

Related Genes

# Gene Symbol Number of hits
1 GLIS3 1 hits

Related Sentences

# PMID Sentence
1 19273592 Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease.
2 19273592 We further show that Glis3 interacts with the transcriptional modulator Wwtr1/TAZ, which itself has been implicated in glomerulocystic kidney disease.
3 19273592 Wwtr1 recognizes a P/LPXY motif in the C terminus of Glis3 and enhances Glis3-mediated transcriptional activation, indicating that Wwtr1 functions as a coactivator of Glis3.
4 19273592 Mutations in the P/LPXY motif abrogate the interaction with Wwtr1 and the transcriptional activity of Glis3, indicating that this motif is part of the transcription activation domain of Glis3.
5 19273592 We propose that localization to the primary cilium and interaction with Wwtr1 are key elements of the Glis3 signaling pathway.
6 19273592 Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease.
7 19273592 We further show that Glis3 interacts with the transcriptional modulator Wwtr1/TAZ, which itself has been implicated in glomerulocystic kidney disease.
8 19273592 Wwtr1 recognizes a P/LPXY motif in the C terminus of Glis3 and enhances Glis3-mediated transcriptional activation, indicating that Wwtr1 functions as a coactivator of Glis3.
9 19273592 Mutations in the P/LPXY motif abrogate the interaction with Wwtr1 and the transcriptional activity of Glis3, indicating that this motif is part of the transcription activation domain of Glis3.
10 19273592 We propose that localization to the primary cilium and interaction with Wwtr1 are key elements of the Glis3 signaling pathway.
11 19273592 Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease.
12 19273592 We further show that Glis3 interacts with the transcriptional modulator Wwtr1/TAZ, which itself has been implicated in glomerulocystic kidney disease.
13 19273592 Wwtr1 recognizes a P/LPXY motif in the C terminus of Glis3 and enhances Glis3-mediated transcriptional activation, indicating that Wwtr1 functions as a coactivator of Glis3.
14 19273592 Mutations in the P/LPXY motif abrogate the interaction with Wwtr1 and the transcriptional activity of Glis3, indicating that this motif is part of the transcription activation domain of Glis3.
15 19273592 We propose that localization to the primary cilium and interaction with Wwtr1 are key elements of the Glis3 signaling pathway.
16 19273592 Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease.
17 19273592 We further show that Glis3 interacts with the transcriptional modulator Wwtr1/TAZ, which itself has been implicated in glomerulocystic kidney disease.
18 19273592 Wwtr1 recognizes a P/LPXY motif in the C terminus of Glis3 and enhances Glis3-mediated transcriptional activation, indicating that Wwtr1 functions as a coactivator of Glis3.
19 19273592 Mutations in the P/LPXY motif abrogate the interaction with Wwtr1 and the transcriptional activity of Glis3, indicating that this motif is part of the transcription activation domain of Glis3.
20 19273592 We propose that localization to the primary cilium and interaction with Wwtr1 are key elements of the Glis3 signaling pathway.
21 19273592 Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease.
22 19273592 We further show that Glis3 interacts with the transcriptional modulator Wwtr1/TAZ, which itself has been implicated in glomerulocystic kidney disease.
23 19273592 Wwtr1 recognizes a P/LPXY motif in the C terminus of Glis3 and enhances Glis3-mediated transcriptional activation, indicating that Wwtr1 functions as a coactivator of Glis3.
24 19273592 Mutations in the P/LPXY motif abrogate the interaction with Wwtr1 and the transcriptional activity of Glis3, indicating that this motif is part of the transcription activation domain of Glis3.
25 19273592 We propose that localization to the primary cilium and interaction with Wwtr1 are key elements of the Glis3 signaling pathway.