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Gene Information

Gene symbol: YWHAZ

Gene name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

HGNC ID: 12855

Synonyms: KCIP-1, 14-3-3-zeta

Related Genes

# Gene Symbol Number of hits
1 MAPK3 1 hits
2 PLA2G1B 1 hits
3 PRKCA 1 hits
4 RAF1 1 hits
5 SDHA 1 hits
6 TBP 1 hits

Related Sentences

# PMID Sentence
1 7559537 The 14.3.3 zeta protein is a ubiquitous and abundant arachidonate-selective acyltransferase and putative phospholipase A2, which self-assembles into dimers and binds to c-Raf-1 and other polypeptides in vitro and in intact cells.
2 7559537 Moreover, expression of recombinant 14.3.3 zeta in COS cells beyond the substantial level of endogenous 14.3.3 protein does not alter endogenous Raf kinase, as judged by the activity of a cotransfected Erk-1 reporter.
3 7559537 The 14.3.3 zeta protein is a ubiquitous and abundant arachidonate-selective acyltransferase and putative phospholipase A2, which self-assembles into dimers and binds to c-Raf-1 and other polypeptides in vitro and in intact cells.
4 7559537 Moreover, expression of recombinant 14.3.3 zeta in COS cells beyond the substantial level of endogenous 14.3.3 protein does not alter endogenous Raf kinase, as judged by the activity of a cotransfected Erk-1 reporter.
5 15909155 Expression of 14-3-3 zeta and interaction with protein kinase C in the rat retina in early diabetes.
6 16085039 We sought to identify candidate control genes by analyzing seven functionally distinct housekeeping genes (B2M, GAPDH, HMBS, HPRT, SDHA, TBP, YWHAZ) for their expression stability and level in the placenta. mRNA isolated from 20 placentae was analyzed for gene expression using RT-PCR.
7 16085039 TBP and SDHA were the most stable, with an average expression stability of M = 0.43, followed by YWHAZ (M = 0.44) > HPRT (M = 0.53) > HMBS (M = 0.57) > GAPDH (M = 0.61) > B2M (M = 0.69).
8 16085039 By using TBP, SDHA and YWHAZ, with greater expression stability than those housekeeping genes commonly used in placenta studies, gene expression profile comparisons will have more sensitivity and specificity.