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Gene Information
Gene symbol: ACVR2A
Gene name: activin A receptor, type IIA
HGNC ID: 173
Synonyms: ACTRII
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ACVR2B | 1 hits |
| 2 | BMP2 | 1 hits |
| 3 | BMPR1A | 1 hits |
| 4 | BMPR1B | 1 hits |
| 5 | BMPR2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16622178 | Upregulation of Id-1 via BMP-2 receptors induces reactive oxygen species in podocytes. |
| 2 | 16622178 | Here, we show the existence of mRNA for BMP-2 and for the BMP receptors BMPR1A, BMPR1B, BMPRII, ACVR1A, ACVR2, and ACVR2B in differentiated mouse podocytes and the protein expression of BMPR1A in human glomerular podocytes. |
| 3 | 16622178 | Recent data indicate that in a myoblastic cell line and in a breast cancer cell line, BMP-2 increases the expression of Id-1, a negative regulator of basic helix-loop-helix transcription factors, but the role of BMP-2 stimulated Id-1 expression in the kidney has not been further characterized. |
| 4 | 16622178 | Here, we show that BMP-2 increases the expression of Id-1 in differentiated podocytes. |
| 5 | 16622178 | The data indicate that BMP-2 may, via an increased expression of Id-1 and an increased generation of ROS, contribute to important cellular functions in podocytes. |