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Gene Information
Gene symbol: AKT3
Gene name: v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
HGNC ID: 393
Synonyms: PKBG, RAC-gamma, PRKBG
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | B4GALT1 | 1 hits |
| 2 | B4GALT7 | 1 hits |
| 3 | CD44 | 1 hits |
| 4 | ERBB2 | 1 hits |
| 5 | GALM | 1 hits |
| 6 | HK2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 32628542 | Previously, we showed that FFSS-induced upregulation of the cyclooxygenase 2 (COX2)-PGE2-prostaglandin E receptor 2 (EP2) axis in podocytes activates Akt-glycogen synthase kinase-3β-β-catenin and MAPK/ERK signaling in response to FFSS. |
| 2 | 32628542 | In the present study, we used previously characterized COX2 [prostaglandin-endoperoxide synthase 2 (Ptgs2)], EP2 (Ptger2), and β1-catenin (Ctnnb1) as "seed genes" from an array data set of four groups analyzed over a time course. |
| 3 | 32628542 | Further validation using Western blot analysis showed increased expression of phosho-Erbb2, phospho-mammalian target of rapamycin (mTOR), CD44, and hexokinase II (Hk2); decreased total Erbb2, galactose mutarotase (Galm), and β-1,4-galactosyltransferase 1 (B4galt1); and unchanged total mTOR and AKT3. |