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Gene Information

Gene symbol: AMOTL1

Gene name: angiomotin like 1

HGNC ID: 17811

Synonyms: JEAP

Related Genes

# Gene Symbol Number of hits
1 ACTN4 1 hits
2 KIAA1274 1 hits
3 LASP1 1 hits
4 PDLIM2 1 hits

Related Sentences

# PMID Sentence
1 21814175 In an effort to discover novel regulatory proteins of the podocyte foot process, we identified and characterized pdlim2, a member of the actin-associated LIM protein subfamily of cytosolic proteins typified by an N-terminal PDZ domain and a C-terminal LIM domain.
2 21814175 Mechanistically, pdlim2 interacts with two actin-associated podocyte proteins, α-actinin-4 and angiomotin-like-1, as shown by immunoprecipitation and yeast two-hybrid analyses.
3 34879092 Then we analyzed the morphological changes of glomeruli and podocytes as well as the expression of the palladin-binding partners Pdlim2, Lasp-1, Amotl1, ezrin and VASP in 6 and 12 months old mice.
4 34879092 Moreover, PodoPalld129-/- of both age showed a severe effacement of podocyte foot processes, a significantly reduced expression of pLasp-1 and Pdlim2, and significantly reduced mRNA expression of Pdlim2 and VASP, three palladin-interacting proteins.