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Gene Information
Gene symbol: ATP6V1C1
Gene name: ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
HGNC ID: 856
Synonyms: VATC, Vma5
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
25374826
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Prorenin receptor (PRR) is a multi-functioning protein possessing at least four different roles: (1) working as a receptor for renin and prorenin producing angiotensin I from angiotensinogen thus enhancing the tissue renin-angiotensin system; (2) inducing intracellular signals when a ligand binds to PRR; (3) participating in the functions of vacuolar proton ATPase; and (4) constituting the Wnt signaling receptor complex.
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2 |
25374826
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This enhances tissue renin-angiotensin system and PRR-mediated mitogen-activated protein kinase signals, resulting in increased injurious molecules such as transforming growth factor-β, cyclooxygenase2, interleukin-1β, and tumor necrosis factor-α ending in diabetic nephropathy progression.
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