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Gene Information
Gene symbol: AXL
Gene name: AXL receptor tyrosine kinase
HGNC ID: 905
Synonyms: UFO, JTK11
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GAS6 | 1 hits |
| 2 | MERTK | 1 hits |
| 3 | PDGFB | 1 hits |
| 4 | RARRES1 | 1 hits |
| 5 | TYRO3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22193389 | The proliferative response coincided with detection of the growth factor Gas6 in the urine and phosphorylation of the Gas6 receptor Axl in the apical membrane of renal tubular cells. |
| 2 | 29511111 | PS exerts multiple biologic effects through the Tyro3, Axl, and Mer (TAM) receptors. |
| 3 | 30429374 | Protein S exerts antiinflammatory and antiapoptotic effects through the activation of TYRO3, AXL, and MER (TAM) receptors. |
| 4 | 30429374 | Mechanistically, TYRO3 expression was suppressed by activation of TNF-α/NF-κB pathway, which may contribute to decreased TYRO3 expression in progressive DKD and FSGS, and TYRO3 signaling conferred antiapoptotic effects through the activation of AKT in podocytes. |
| 5 | 30716432 | Poricoic acid A enhances melatonin inhibition of AKI-to-CKD transition by regulating Gas6/AxlNFκB/Nrf2 axis. |
| 6 | 30716432 | Our results further showed that treatment with melatonin and PAA ameliorated renal fibrosis and podocyte injury by attenuating oxidative stress and inflammation via regulation of nuclear factor-kappa B (NF-κB) and nuclear factor-erythroid-2-related factor 2 (Nrf2) pathways in IRI rats. |
| 7 | 30716432 | Melatonin and PAA protected against AKI-to-CKD transition by regulating growth arrest-specific 6 (Gas6)/AxlNFκB/Nrf2 signaling cascade. |
| 8 | 30716432 | Melatonin and PAA initiallyupregulated Gas6/Axl signaling to reduce oxidative stress and inflammation in AKI and subsequently downregulated Gas6/Axl signaling to attenuate renal fibrosis and progression to CKD. |
| 9 | 30716432 | Poricoic acid A enhances melatonin-mediated inhibition of AKI-to-CKD transition by the regulating Gas6/AxlNFκB/Nrf2 signaling cascade. |
| 10 | 34147551 | Retinoic acid receptor responder1 promotes development of glomerular diseases via the Nuclear Factor-κB signaling pathway. |
| 11 | 34147551 | Mechanistically, Rarres1 promoted inflammation and fibrosis via transcription factor Nuclear Factor-κB signaling pathway by activating receptor tyrosine kinase Axl. |
| 12 | 34939009 | Mesangioproliferative Kidney Diseases and Platelet-Derived Growth Factor-Mediated AXL Phosphorylation. |