Ignet

Gene symbol: BBC3

Gene name: BCL2 binding component 3

HGNC ID: 17868

Synonyms: JFY1, PUMA

Related Genes

Related Sentences

#	PMID	Sentence
1	25411797	Therefore, in the present study, we evaluated the effect of p53 deSUMOylation, which is regulated by sentrin/SUMO-specific protease 1 (SENP1), on podocyte apoptosis.
2	25411797	Moreover, SENP1 knockdown results in the accumulation of SUMOylated p53 protein and the increased expression of the p53 target pro-apoptotic genes, BAX, Noxa and PUMA, in podocytes during PAN stimulation.
3	25411797	Thus, SENP1 may be essential for preventing podocyte apoptosis, at least partly through regulating the functions of p53 protein via deSUMOylation.