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Gene Information
Gene symbol: BMP4
Gene name: bone morphogenetic protein 4
HGNC ID: 1071
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CALM1 | 1 hits |
| 2 | CASP3 | 1 hits |
| 3 | CDH11 | 1 hits |
| 4 | FBLN2 | 1 hits |
| 5 | GDNF | 1 hits |
| 6 | NOG | 1 hits |
| 7 | NPHS1 | 1 hits |
| 8 | NTN4 | 1 hits |
| 9 | SMAD3 | 1 hits |
| 10 | SNAI2 | 1 hits |
| 11 | TNC | 1 hits |
| 12 | VEGFA | 1 hits |
| 13 | VEGFB | 1 hits |
| 14 | YWHAB | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18272846 | To examine the role of BMP4 in glomerular morphogenesis, we generated transgenic mice with altered BMP4 function in podocytes by conferring tissue-specificity with the nephrin (Nphs1) promoter. |
| 2 | 18272846 | However, in vitro studies with metanephroi failed to demonstrate a direct interaction between BMP4 or Noggin and VEGF in podocytes. |
| 3 | 18272846 | To examine the role of BMP4 in glomerular morphogenesis, we generated transgenic mice with altered BMP4 function in podocytes by conferring tissue-specificity with the nephrin (Nphs1) promoter. |
| 4 | 18272846 | However, in vitro studies with metanephroi failed to demonstrate a direct interaction between BMP4 or Noggin and VEGF in podocytes. |
| 5 | 22677342 | The renal protein expression of renin and angiotensin II was reduced at birth day and increased at weaning. |
| 6 | 22677342 | Maternal DEHP exposure also led to reduced mRNA expression of some renal development involved genes at birth day, including Foxd1, Gdnf, Pax2 and Wnt11. |
| 7 | 22677342 | While, the mRNA expression of some genes was raised, including Bmp4, Cdh11, Calm1 and Ywhab. |
| 8 | 30158674 | Podocyte-specific Bmp4-overexpressing mice displayed increased kidney BMP4 expression and mesangial matrix expansion but decreased nephrin expression and numbers of WT1-positive cells. |
| 9 | 30158674 | BMP4 decreased nephrin expression but increased cleaved caspase-3 levels. p38 suppression inhibited caspase-3 activation. |
| 10 | 30158674 | Podocyte-specific Bmp4-overexpressing mice displayed increased kidney BMP4 expression and mesangial matrix expansion but decreased nephrin expression and numbers of WT1-positive cells. |
| 11 | 30158674 | BMP4 decreased nephrin expression but increased cleaved caspase-3 levels. p38 suppression inhibited caspase-3 activation. |
| 12 | 31150422 | Involvement of Elf3 on Smad3 activation-dependent injuries in podocytes and excretion of urinary exosome in diabetic nephropathy. |
| 13 | 31150422 | The bone morphogenetic protein 4 (BMP4) significantly regulated activation of RII-Smad3 signalings (P<0.05). |
| 14 | 31150422 | Induction of Elf3 and activation of RII-Smad3 signaling, leading to a decrease in WT1 expression, were observed in podocytes in diabetic human kidneys. |
| 15 | 31461442 | In the podocytes we observed upregulation of many genes related to the Tgfβ family/pathway, including Gdnf, Tgfβ1, Tgfβ2, Snai2, Vegfb, Bmp4, and Tnc. |
| 16 | 31622881 | Trajectory analysis identified transient developmental gene expression, predicting precursors or mature podocytes express FBLN2, BMP4, or NTN4, in conjunction with recruitment, differentiation, and modeling of vascular and mesangial cell types into a functional filter. |