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Gene Information
Gene symbol: BRPF1
Gene name: bromodomain and PHD finger containing, 1
HGNC ID: 14255
Synonyms: BR140
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BRD4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 31325480 | BRD4 contributes to high-glucose-induced podocyte injury by modulating Keap1/Nrf2/ARE signaling. |
| 2 | 31325480 | Bromodomain-containing protein 4 (BRD4) has emerged as a critical regulator for cell injury. |
| 3 | 31325480 | Moreover, BRD4 inhibition potentiated nuclear factor (erythroid-derived 2)-like 2 (Nrf2) signaling associated with suppression of Kelch-like ECH-associated protein (Keap1). |
| 4 | 31325480 | BRD4 inhibition promoted Nrf2 nuclear translocation and upregulated the transcriptional activity of Nrf2/antioxidant response element (ARE). |
| 5 | 31325480 | Overall, these results suggest that BRD4 inhibition confers cytoprotection against HG injury in podocytes through potentiation of Nrf2/ARE antioxidant signaling. |
| 6 | 31325480 | This finding implicates BRD4/Nrf2/ARE signaling in the pathogenesis of diabetic nephropathy. |