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Gene Information

Gene symbol: CADM1

Gene name: cell adhesion molecule 1

HGNC ID: 5951

Synonyms: NECL2, ST17, BL2, SYNCAM, IGSF4A, Necl-2, SYNCAM1, RA175

Related Genes

# Gene Symbol Number of hits
1 CCL2 1 hits
2 ESAM 1 hits
3 ICAM1 1 hits
4 ICAM2 1 hits
5 KDR 1 hits
6 TNF 1 hits
7 VEGFA 1 hits
8 VWF 1 hits

Related Sentences

# PMID Sentence
1 12138137 A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development.
2 12138137 The Wilms' tumor suppressor gene WT1 encodes a zinc finger protein that is required for urogenital development.
3 12138137 Platelet endothelial cell adhesion molecule-1 expression was greatly reduced on glomerular endothelial cells of transgenic kidneys.
4 16557232 Cells were selected, cloned, and then characterized by light and electron microscopy (EM), response to vascular endothelial growth factor (VEGF), and tumour necrosis factor (TNF)alpha, expression of endothelial markers by focused gene array, immunofluorescence and Western blotting, and formation and behaviour of monolayers.
5 16557232 EM demonstrated fenestrations, increased in number by VEGF. mRNA analysis confirmed expression of the endothelial markers platelet endothelial cell adhesion molecule 1, intercellular adhesion molecule 2, VEGF receptor 2, and von Willebrand factor, validated by immunofluorescence and Western blotting.
6 16557232 CiGEnC also expressed Tie2, and TNFalpha upregulated E-selectin.
7 18220690 Inflammatory markers such as Interleukin-18 and Tumor Necrosis Factor (TNF)-alpha are increased in the serum of patients with diabetes and DN.
8 18220690 Experimental animal models have recently provided evidence that some acute phase markers of inflammation such as intracellular cell adhesion molecule-1 (ICAM-1), TNF-alpha and Monocytes Chemoattractant Protein-1 (MCP-1) may have a causative role in the development of DN.