Ignet

Gene Information

Gene symbol: CD37

Gene name: CD37 molecule

HGNC ID: 1666

Synonyms: TSPAN26

Related Genes

#	Gene Symbol	Number of hits
1	IL10	1 hits
2	IL6	1 hits
3	TNF	1 hits
4	TSPAN32	1 hits

Related Sentences

#	PMID	Sentence
1	29551516	Interleukin-6 is essential for glomerular immunoglobulin A deposition and the development of renal pathology in Cd37-deficient mice.
2	29551516	Deficiency of CD37, a leukocyte-specific tetraspanin, leads to spontaneous development of renal pathology resembling IgAN.
3	29551516	Circulating interleukin (IL)-6 levels, but not tumor necrosis factor-α or IL-10, were elevated in Cd37^-/- mice compared to wild-type mice after lipopolysaccharide treatment.
4	29551516	To evaluate the role of IL-6 in the pathogenesis of accelerated renal pathology in Cd37^-/-mice, we generated Cd37xIl6 double-knockout mice.
5	29551516	Moreover, kidneys of Cd37^-/- mice showed more mesangial proliferation, endothelial cell activation, podocyte activation, and segmental podocyte foot process effacement compared to the double-knockout mice, emphasizing that IL-6 mediates renal pathology in Cd37^-/- mice.
6	29551516	Thus, our study indicates that CD37 may protect against IgA nephropathy by inhibition of the IL-6 pathway.
7	29551516	Interleukin-6 is essential for glomerular immunoglobulin A deposition and the development of renal pathology in Cd37-deficient mice.
8	29551516	Deficiency of CD37, a leukocyte-specific tetraspanin, leads to spontaneous development of renal pathology resembling IgAN.
9	29551516	Circulating interleukin (IL)-6 levels, but not tumor necrosis factor-α or IL-10, were elevated in Cd37^-/- mice compared to wild-type mice after lipopolysaccharide treatment.
10	29551516	To evaluate the role of IL-6 in the pathogenesis of accelerated renal pathology in Cd37^-/-mice, we generated Cd37xIl6 double-knockout mice.
11	29551516	Moreover, kidneys of Cd37^-/- mice showed more mesangial proliferation, endothelial cell activation, podocyte activation, and segmental podocyte foot process effacement compared to the double-knockout mice, emphasizing that IL-6 mediates renal pathology in Cd37^-/- mice.
12	29551516	Thus, our study indicates that CD37 may protect against IgA nephropathy by inhibition of the IL-6 pathway.
13	29551516	Interleukin-6 is essential for glomerular immunoglobulin A deposition and the development of renal pathology in Cd37-deficient mice.
14	29551516	Deficiency of CD37, a leukocyte-specific tetraspanin, leads to spontaneous development of renal pathology resembling IgAN.
15	29551516	Circulating interleukin (IL)-6 levels, but not tumor necrosis factor-α or IL-10, were elevated in Cd37^-/- mice compared to wild-type mice after lipopolysaccharide treatment.
16	29551516	To evaluate the role of IL-6 in the pathogenesis of accelerated renal pathology in Cd37^-/-mice, we generated Cd37xIl6 double-knockout mice.
17	29551516	Moreover, kidneys of Cd37^-/- mice showed more mesangial proliferation, endothelial cell activation, podocyte activation, and segmental podocyte foot process effacement compared to the double-knockout mice, emphasizing that IL-6 mediates renal pathology in Cd37^-/- mice.
18	29551516	Thus, our study indicates that CD37 may protect against IgA nephropathy by inhibition of the IL-6 pathway.
19	29551516	Interleukin-6 is essential for glomerular immunoglobulin A deposition and the development of renal pathology in Cd37-deficient mice.
20	29551516	Deficiency of CD37, a leukocyte-specific tetraspanin, leads to spontaneous development of renal pathology resembling IgAN.
21	29551516	Circulating interleukin (IL)-6 levels, but not tumor necrosis factor-α or IL-10, were elevated in Cd37^-/- mice compared to wild-type mice after lipopolysaccharide treatment.
22	29551516	To evaluate the role of IL-6 in the pathogenesis of accelerated renal pathology in Cd37^-/-mice, we generated Cd37xIl6 double-knockout mice.
23	29551516	Moreover, kidneys of Cd37^-/- mice showed more mesangial proliferation, endothelial cell activation, podocyte activation, and segmental podocyte foot process effacement compared to the double-knockout mice, emphasizing that IL-6 mediates renal pathology in Cd37^-/- mice.
24	29551516	Thus, our study indicates that CD37 may protect against IgA nephropathy by inhibition of the IL-6 pathway.
25	29551516	Interleukin-6 is essential for glomerular immunoglobulin A deposition and the development of renal pathology in Cd37-deficient mice.
26	29551516	Deficiency of CD37, a leukocyte-specific tetraspanin, leads to spontaneous development of renal pathology resembling IgAN.
27	29551516	Circulating interleukin (IL)-6 levels, but not tumor necrosis factor-α or IL-10, were elevated in Cd37^-/- mice compared to wild-type mice after lipopolysaccharide treatment.
28	29551516	To evaluate the role of IL-6 in the pathogenesis of accelerated renal pathology in Cd37^-/-mice, we generated Cd37xIl6 double-knockout mice.
29	29551516	Moreover, kidneys of Cd37^-/- mice showed more mesangial proliferation, endothelial cell activation, podocyte activation, and segmental podocyte foot process effacement compared to the double-knockout mice, emphasizing that IL-6 mediates renal pathology in Cd37^-/- mice.
30	29551516	Thus, our study indicates that CD37 may protect against IgA nephropathy by inhibition of the IL-6 pathway.
31	29551516	Interleukin-6 is essential for glomerular immunoglobulin A deposition and the development of renal pathology in Cd37-deficient mice.
32	29551516	Deficiency of CD37, a leukocyte-specific tetraspanin, leads to spontaneous development of renal pathology resembling IgAN.
33	29551516	Circulating interleukin (IL)-6 levels, but not tumor necrosis factor-α or IL-10, were elevated in Cd37^-/- mice compared to wild-type mice after lipopolysaccharide treatment.
34	29551516	To evaluate the role of IL-6 in the pathogenesis of accelerated renal pathology in Cd37^-/-mice, we generated Cd37xIl6 double-knockout mice.
35	29551516	Moreover, kidneys of Cd37^-/- mice showed more mesangial proliferation, endothelial cell activation, podocyte activation, and segmental podocyte foot process effacement compared to the double-knockout mice, emphasizing that IL-6 mediates renal pathology in Cd37^-/- mice.
36	29551516	Thus, our study indicates that CD37 may protect against IgA nephropathy by inhibition of the IL-6 pathway.