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Gene Information
Gene symbol: CDK5R2
Gene name: cyclin-dependent kinase 5, regulatory subunit 2 (p39)
HGNC ID: 1776
Synonyms: p39nck5ai, P39, NCK5AI
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCNI | 1 hits |
| 2 | CDK5 | 1 hits |
| 3 | CDK5R1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 25500740 | Cyclin I and p35 determine the subcellular distribution of Cdk5. |
| 2 | 25500740 | The kinase activity, half-life, and substrate specificity of Cdk5 largely depend on specific activators, such as p25, p35, p39, and cyclin I. |
| 3 | 25500740 | Cdk5 localization was analyzed in murine kidney and brain slices of wild-type and cyclin I- and/or p35-null mice by immunohistochemistry and in cultured mouse podocytes using immunofluorescence labeling, as well as cell fractionation experiments. |
| 4 | 25500740 | The predominance of cyclin I mediates the nuclear localization of Cdk5, whereas the predominance of p35 results in a membranous localization of Cdk5. |
| 5 | 25500740 | These findings were further substantiated by overexpression of cyclin I and p35 with altered targeting characteristics in human embryonic kidney 293T cells. |