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Gene Information

Gene symbol: COMP

Gene name: cartilage oligomeric matrix protein

HGNC ID: 2227

Synonyms: MED, THBS5

Related Genes

# Gene Symbol Number of hits
1 ANGPT1 1 hits

Related Sentences

# PMID Sentence
1 24459518 Thus, we evaluated the protective effect of cartilage oligomeric matrix protein-angiopoietin-1 (COMP-Ang1) in unilateral ureteral obstruction (UUO)-induced renal fibrosis, cyclosporine A (CsA)-induced renal injury, and the diabetic nephropathy model.
2 24459518 COMP-Ang1 treatment decreased monocyte/macrophage infiltration, tissue levels of transforming growth factor β1, and Smad 2/3 phosphorylation and increased Smad 7 in the obstructed kidney.
3 24459518 COMP-Ang1 administration also decreased increased macrophage infiltration, adhesion molecule expression, TGF-β1, and Smad 2/3 levels in CsA-treated kidneys, while increasing Smad 7 levels.