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Gene Information
Gene symbol: COMP
Gene name: cartilage oligomeric matrix protein
HGNC ID: 2227
Synonyms: MED, THBS5
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
24459518
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Thus, we evaluated the protective effect of cartilage oligomeric matrix protein-angiopoietin-1 (COMP-Ang1) in unilateral ureteral obstruction (UUO)-induced renal fibrosis, cyclosporine A (CsA)-induced renal injury, and the diabetic nephropathy model.
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2 |
24459518
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COMP-Ang1 treatment decreased monocyte/macrophage infiltration, tissue levels of transforming growth factor β1, and Smad 2/3 phosphorylation and increased Smad 7 in the obstructed kidney.
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3 |
24459518
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COMP-Ang1 administration also decreased increased macrophage infiltration, adhesion molecule expression, TGF-β1, and Smad 2/3 levels in CsA-treated kidneys, while increasing Smad 7 levels.
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