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Gene Information
Gene symbol: CR2
Gene name: complement component (3d/Epstein Barr virus) receptor 2
HGNC ID: 2336
Synonyms: CD21
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | C1R | 1 hits |
| 2 | C3AR1 | 1 hits |
| 3 | C4B | 1 hits |
| 4 | C4BPA | 1 hits |
| 5 | C5AR1 | 1 hits |
| 6 | CD46 | 1 hits |
| 7 | CD55 | 1 hits |
| 8 | CD59 | 1 hits |
| 9 | CFB | 1 hits |
| 10 | CFD | 1 hits |
| 11 | CFH | 1 hits |
| 12 | CFI | 1 hits |
| 13 | CR1 | 1 hits |
| 14 | MASP1 | 1 hits |
| 15 | TDGF3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 2418113 | Characterization of the human glomerular C3 receptor as the C3b/C4b complement type one (CR1) receptor. |
| 2 | 2418113 | The functional and immunochemical characteristics of the human glomerular C3 receptor were investigated by adherence of sheep erythrocytes (Es) coated with defined C3 fragments and by using polyclonal and/or monoclonal antibodies directed against epitopes expressed on complement receptors CR1, CR2, and CR3. |
| 3 | 2418113 | Glomerular CR1 shares the functional antigenic and biochemical properties of the C3b/C4b CR1 receptor of peripheral blood cells. |
| 4 | 2941021 | Decreased expression of the C3b/C4b receptor (CR1) and the C3d receptor (CR2) on B lymphocytes and of CR1 on neutrophils of patients with systemic lupus erythematosus. |
| 5 | 2941021 | The expression of CR1 correlated with that of CR2 among patients (r = 0.63; P less than 0.01) but not with the expression of CR2 among normal individuals (r = 0.36; P greater than 0.1). |
| 6 | 2941021 | Decreased expression of the C3b/C4b receptor (CR1) and the C3d receptor (CR2) on B lymphocytes and of CR1 on neutrophils of patients with systemic lupus erythematosus. |
| 7 | 2941021 | The expression of CR1 correlated with that of CR2 among patients (r = 0.63; P less than 0.01) but not with the expression of CR2 among normal individuals (r = 0.36; P greater than 0.1). |
| 8 | 2989379 | Human complement receptors for C3b (CR1) and C3d (CR2). |
| 9 | 6227098 | The factor H-like cofactor activity of the C3b receptor promotes the cleavage of bound C3b to iC3b, C3c and C3d, g, reactions that may enhance the clearance of circulating immune complexes and the generation of ligands for CR2 and CR3. |
| 10 | 25291704 | These receptors, which are termed CR1, CR2 and CR3, reside on lymphocytes, myelomonocytic cells, erythrocytes and renal podocytes. |
| 11 | 27043537 | Both primary cultured podocytes and immortalized podocytes expressed the complement factors C1q, C1r, C2, C3, C7, MASP, CFI, DAF, CD59, C4bp, CD46, Protein S, CR2, C1qR, C3aR, C5aR, and Crry (17/32), whereas C4, CFB, CFD, C5, C6, C8, C9, MBL1, and MBL2 (9/32) complement factors were not expressed. |
| 12 | 27043537 | Podocyte complement gene expression was affected by several factors (puromycin aminonucleoside (PAN), angiotensin II (Ang II), interleukin-6 (IL-6), and transforming growth factor-β (TGF-β)). |