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Gene Information
Gene symbol: CRELD2
Gene name: cysteine-rich with EGF-like domains 2
HGNC ID: 28150
Synonyms: MGC11256
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | EGF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 29212948 | Cysteine-rich with EGF-like domains 2 (CRELD2) is a newly identified protein that is induced and secreted under ER stress. |
| 2 | 30099615 | Mutations in nephrin (NPHS1), podocin (NPHS2), laminin β2 (LAMB2), and α-actinin-4 (ACTN4) have been shown to induce ER stress in HEK293 cells and podocytes in hereditary nephrotic syndromes; various founder mutations in collagen IV α chains (COL4A) have been demonstrated to activate podocyte ER stress in collagen IV nephropathies; and mutations in uromodulin (UMOD) have been reported to trigger tubular ER stress in autosomal dominant tubulointerstitial kidney disease. |
| 3 | 30099615 | Recently, we have identified mesencephalic astrocyte-derived neurotrophic factor (MANF) and cysteine-rich with EGF-like domains 2 (CRELD2) as urinary ER stress biomarkers in ER stress-mediated kidney diseases. |