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Gene Information

Gene symbol: CSRP3

Gene name: cysteine and glycine-rich protein 3 (cardiac LIM protein)

HGNC ID: 2472

Synonyms: CLP, MLP, CMD1M

Related Genes

# Gene Symbol Number of hits
1 LMX1B 1 hits
2 PDLIM5 1 hits
3 WTIP 1 hits

Related Sentences

# PMID Sentence
1 14736876 A yeast two-hybrid assay identified a novel, WT1-interacting protein (WTIP) that maps to human chromosome 19q13.1, a region with genes linked to familial focal segmental glomerulosclerosis.
2 14736876 The domain structure of WTIP is similar to the zyxin subfamily of cytosolic LIM domain-containing proteins, which contain three carboxyl-terminal LIM protein-protein interaction domains and a proline-rich, pre-LIM region with a nuclear export signal.
3 14736876 Other LIM domain-containing proteins (zyxin and mouse muscle LIM protein) did not interact with WT1 in two-hybrid assays, and WTIP did not interact with an unrelated transcription factor, LMX1B.
4 14736876 The partial WTIP clone, which interacted with WTIP in the two-hybrid assay, co-localized with WT1 in nuclei, co-precipitated with WT1, and inhibited WT1-dependent transcriptional activation of the amphiregulin promoter.
5 14736876 Epitope-tagged WTIP co-localized with the adaptor protein CD2AP (CMS) in podocyte actin spots and with Mena at cell-cell junctions.
6 30829647 Cardiac LIM protein was a CA/CPR-specific filtrate component.
7 30829647 Cardiac arrest induced plasma release of cardiac LIM protein in mice and critically ill human cardiac arrest survivors, and administration of recombinant cardiac LIM protein to mice altered renal function.
8 30829647 Cardiac LIM protein was a CA/CPR-specific filtrate component.
9 30829647 Cardiac arrest induced plasma release of cardiac LIM protein in mice and critically ill human cardiac arrest survivors, and administration of recombinant cardiac LIM protein to mice altered renal function.