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Gene Information

Gene symbol: CXCL2

Gene name: chemokine (C-X-C motif) ligand 2

HGNC ID: 4603

Synonyms: SCYB2, GROb, MIP-2a, MGSA-b, CINC-2a

Related Genes

# Gene Symbol Number of hits
1 CXCL1 1 hits
2 DDIT3 1 hits
3 IL10 1 hits
4 IL18 1 hits
5 IL1RN 1 hits
6 IL6 1 hits
7 NT5E 1 hits
8 VEGFA 1 hits

Related Sentences

# PMID Sentence
1 21304992 Cells immunopositive for Wilms tumor 1 (podocyte marker) and interleukin-1 family, member 6 (damaged DT and CD marker) in the kidney significantly decreased and increased in BXSB versus B6, respectively.
2 21304992 In the PCR array analysis of inflammatory cytokines and chemokines, Il10, Cxcl2, C3, and Il1rn showed relatively higher expression in BXSB kidneys than in B6 kidneys.
3 22666342 We observed autoimmune inflammation in CD73(-/-)mice with glomerulitis and peritubular capillaritis, showing glomerular deposition of IgG and C3 and enhanced presence of CD11b, CD8, CD25 as well as GR-1-positive cells in the interstitium.
4 22666342 Vascular inflammation was associated with enhanced serum levels of the cytokines IL-18 and TNF-α as well as VEGF and the chemokine MIP-2 (CXCL-2) in CD73(-/-)mice, whereas chemokines and cytokines in the kidney tissue were unaltered or reduced.
5 23235477 Unexpectedly, while Toll-like receptor 4 (TLR4) expression levels were comparable in kidneys of CHOP(-/-) and wild-type (WT) mice, CHOP(-/-) mice developed more severe AKI after LPS injection.
6 23235477 Additionally, the kidneys of LPS-treated CHOP(-/-) mice had a more prominent increase in NF-κB activation and further upregulation of proinflammatory genes, i.e., c-x-c motif ligand 1 (CXCL-1), macrophage inflammatory protein-2 (MIP-2), and IL-6.