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Gene Information
Gene symbol: DDT
Gene name: D-dopachrome tautomerase
HGNC ID: 2732
Synonyms: DDCT
Related Genes
Related Sentences
# |
PMID |
Sentence |
1 |
26441987
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CD74 (invariant MHC class II) regulates protein trafficking and is a receptor for macrophage migration inhibitory factor (MIF) and d-dopachrome tautomerase (d-DT/MIF-2).
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2 |
26441987
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MIF activates CD74 to increase inflammatory cytokines in podocytes and tubular cells and proliferation in glomerular parietal epithelial cells and cyst cells.
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3 |
26441987
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MIF overexpression promotes while MIF targeting protects from experimental glomerular injury and kidney cysts, and interference with MIF/CD74 signaling or CD74 deficiency protected from crescentic glomerulonephritis.
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