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Gene Information
Gene symbol: DUSP4
Gene name: dual specificity phosphatase 4
HGNC ID: 3070
Synonyms: HVH2, MKP-2, TYP
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CASP3 | 1 hits |
| 2 | JUN | 1 hits |
| 3 | MAPK1 | 1 hits |
| 4 | MAPK8 | 1 hits |
| 5 | NOX4 | 1 hits |
| 6 | PRKCA | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 30862678 | Dual specificity phosphatases (DUSPs) are a family of phosphatases mainly responsible for MAPK inhibition. |
| 2 | 30862678 | Diabetes-induced DUSP4 reduction enhanced p38 and c-Jun N-terminal kinase (JNK) activity and podocyte dysfunction. |
| 3 | 30862678 | The overexpression of DUSP4 prevented the activation of p38, JNK, caspase 3/7 activity, and NADPH oxidase 4 expression induced by high glucose level exposure. |
| 4 | 30862678 | These morphological changes were associated with profound podocyte foot process effacement, cell death, and sustained p38 and JNK activation. |
| 5 | 30862678 | Moreover, inhibition of protein kinase C-δ prevented DUSP4 expression decline and p38/JNK activation in the podocytes and renal cortex of diabetic mice. |
| 6 | 30862678 | Dual specificity phosphatases (DUSPs) are a family of phosphatases mainly responsible for MAPK inhibition. |
| 7 | 30862678 | Diabetes-induced DUSP4 reduction enhanced p38 and c-Jun N-terminal kinase (JNK) activity and podocyte dysfunction. |
| 8 | 30862678 | The overexpression of DUSP4 prevented the activation of p38, JNK, caspase 3/7 activity, and NADPH oxidase 4 expression induced by high glucose level exposure. |
| 9 | 30862678 | These morphological changes were associated with profound podocyte foot process effacement, cell death, and sustained p38 and JNK activation. |
| 10 | 30862678 | Moreover, inhibition of protein kinase C-δ prevented DUSP4 expression decline and p38/JNK activation in the podocytes and renal cortex of diabetic mice. |
| 11 | 30862678 | Dual specificity phosphatases (DUSPs) are a family of phosphatases mainly responsible for MAPK inhibition. |
| 12 | 30862678 | Diabetes-induced DUSP4 reduction enhanced p38 and c-Jun N-terminal kinase (JNK) activity and podocyte dysfunction. |
| 13 | 30862678 | The overexpression of DUSP4 prevented the activation of p38, JNK, caspase 3/7 activity, and NADPH oxidase 4 expression induced by high glucose level exposure. |
| 14 | 30862678 | These morphological changes were associated with profound podocyte foot process effacement, cell death, and sustained p38 and JNK activation. |
| 15 | 30862678 | Moreover, inhibition of protein kinase C-δ prevented DUSP4 expression decline and p38/JNK activation in the podocytes and renal cortex of diabetic mice. |