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Gene Information
Gene symbol: DYNC1H1
Gene name: dynein, cytoplasmic 1, heavy chain 1
HGNC ID: 2961
Synonyms: Dnchc1, HL-3, p22, DHC1
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
28211114
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The old rats exhibited a dysregulation of the expression of proteins related to oxidative stress and inflammation in the kidneys, and MLB administration significantly reduced the protein expression of major subunits of nicotinamide adenine dinucleotide phosphate oxidase (Nox4 and p22phox ), phospho-p38, nuclear factor-kappa B p65, cyclooxygenase-2, and inducible nitric oxide synthase.
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2 |
28211114
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In addition, MLB-treated old rats showed lower levels of senescence-related proteins such as p16, ADP-ribosylation factor 6, p53, and p21 through effects on the mitogen-activated protein kinase pathway.
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