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Gene Information
Gene symbol: FCGR2B
Gene name: Fc fragment of IgG, low affinity IIb, receptor (CD32)
HGNC ID: 3618
Synonyms: CD32, CD32B
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
12408047
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This autoimmunity may result from loss of a feedback inhibitory pathway in which Lyn phosphorylates CD22, triggering recruitment of the tyrosine phosphatase SHP-1 to the plasma membrane, which then dampens BCR signaling.
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2 |
12408047
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Loss of Lyn also compromises an inhibitory pathway involving Fc gamma RIIb and SHIP, an inositol phosphatase.
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3 |
24477164
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Analysis of the renal levels of the Fc gamma receptor (Fcgr) and interferon-activated gene 200 (Ifi200) family genes, which are MPGN candidate genes localized to the telomeric region of chromosome 1 (Chr.1), showed that Fcgr2b levels decreased, whereas Fcgr3 and Ifi202b levels increased in female BXSB/MpJ mice compared with healthy C57BL/6 mice.
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