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Gene Information
Gene symbol: GAS1
Gene name: growth arrest-specific 1
HGNC ID: 4165
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD24 | 1 hits |
| 2 | CD36 | 1 hits |
| 3 | DIAPH1 | 1 hits |
| 4 | GPI | 1 hits |
| 5 | NCAM1 | 1 hits |
| 6 | NES | 1 hits |
| 7 | SIX1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 23254899 | Growth arrest-specific protein-1 (GAS1) is a GPI-anchored protein which is highly expressed in embryonic mouse fibroblasts and inhibits their proliferation. |
| 2 | 28315934 | We found that diabetes reduced the expression of Gas1 and increased the expression of progenitor markers like NCAM, CD24, and SIX1/2, and mesenchymal markers like PAX2 in the Bowman's capsule. |
| 3 | 30132346 | Deletion of the formin Diaph1 protects from structural and functional abnormalities in the murine diabetic kidney. |
| 4 | 30132346 | Diaphanous 1 (DIAPH1), a member of the formin family, binds to the cytoplasmic domain of the receptor for advanced glycation end products (RAGE) and is required for RAGE signal transduction. |
| 5 | 30132346 | After 6 mo of hyperglycemia, diabetic Diaph1-/- mice displayed significantly reduced mesangial sclerosis, podocyte effacement, glomerular basement thickening, and urinary albumin-to-creatinine ratio compared with diabetic mice expressing Diaph1. |
| 6 | 30132346 | In glomerular isolates, expression of two genes linked to podocyte stress, growth arrest-specific 1 ( Gas1) and cluster of differentiation 36 ( Cd36), was significantly attenuated in diabetic Diaph1-/- mice compared with controls, in parallel with significantly higher levels of nestin (Nes) mRNA, a podocyte marker. |