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PMID |
Sentence |
1 |
23254899
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Growth arrest-specific protein-1 (GAS1) is a GPI-anchored protein which is highly expressed in embryonic mouse fibroblasts and inhibits their proliferation.
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2 |
27504461
|
Soluble urokinase-type plasminogen activator receptor (suPAR) is a soluble form of uPAR, which is a membrane-bound protein linked to GPI in various immunologically active cells, including podocytes.
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3 |
31487557
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Sphingomyelinase phosphodiesterase like 3b (SMPDL3b) is a glycosylphosphatidylinositol (GPI) anchored protein in the plasma membrane (PM) and determines membrane fluidity in macrophages.
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4 |
31487557
|
This observation lead us to investigate if SMPDL3b controls C1P availability in human podocytes by interfering with ceramide kinase (CERK) expression and function.
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5 |
31487557
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We found that SMPDL3b interacts with CERK and can bind to C1P in vitro.
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6 |
31487557
|
Furthermore, CERK expression is reduced when SMPDL3b expression is silenced.
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7 |
31487557
|
These observations led us to propose that one of the mechanisms by which SMPDL3b influences the amount of C1P available in the podocytes is by interfering with the function of CERK thereby maintaining a balance in the levels of the C1P in podocytes.
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8 |
33763084
|
Murine T cells express the GPI-anchored ADP-ribosyltransferase 2.2 (ARTC2.2) on the cell surface.
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