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Gene Information
Gene symbol: ICOSLG
Gene name: inducible T-cell co-stimulator ligand
HGNC ID: 17087
Synonyms: KIAA0653, GL50, B7-H2, B7RP-1, B7H2, B7RP1, ICOS-L, CD275
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD86 | 1 hits |
| 2 | ICOS | 1 hits |
| 3 | RLTPR | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 30747722 | Here we report what we believe is a novel renoprotective role for the inducible costimulator ligand (ICOSL) in early kidney disease through its selective binding to podocyte αvβ3 integrin. |
| 2 | 30747722 | Specifically, ICOSL contains the arginine-glycine-aspartate (RGD) motif, which allowed for a high-affinity and selective binding to αvβ3 and modulation of podocyte adhesion. |
| 3 | 30747722 | Here we report what we believe is a novel renoprotective role for the inducible costimulator ligand (ICOSL) in early kidney disease through its selective binding to podocyte αvβ3 integrin. |
| 4 | 30747722 | Specifically, ICOSL contains the arginine-glycine-aspartate (RGD) motif, which allowed for a high-affinity and selective binding to αvβ3 and modulation of podocyte adhesion. |
| 5 | 33370294 | Podocyte-specific knockout of the neonatal Fc receptor (FcRn) results in differential protection depending on the model of glomerulonephritis. |
| 6 | 33370294 | In traditional APCs, the neonatal Fc receptor (FcRn) is required for antigen presentation and global knockout of FcRn protects against glomerulonephritis. |
| 7 | 33370294 | Interferon gamma (IFNγ) induced MHCII expression in both WT and KO podocytes but did not change CD80 expression. |
| 8 | 33370294 | Neither WT nor KO expressed CD86 or inducible costimulatory ligand (ICOSL) at baseline or with IFNγ. |