Gene Information
Gene symbol: IFI16
Gene name: interferon, gamma-inducible protein 16
HGNC ID: 5395
Synonyms: IFNGIP1, PYHIN2
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
31664093
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We demonstrate that maximal APOL1 expression also requires the activation of type I IFN receptor (IFNAR) and STAT1 signaling triggered by IFNβ produced in response to nsDNA, or by exogenous IFNβ.
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2 |
31664093
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Finally, we show that STAT1 activation is sufficient to upregulate IFI16, subsequently boosting APOL1 expression through a positive feedback mechanism.
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