Ignet
Search (e.g., vaccine, IFNG): Help
About
Home
Introduction
Statistics
Programs
Dignet
Gene
GenePair
BioSummarAI
Help & Docs
Documents
Help
FAQs
Links
Acknowledge
Disclaimer
Contact Us
UM Logo

UMMS Logo

UMMS Logo

Gene Information

Gene symbol: IL15

Gene name: interleukin 15

HGNC ID: 5977

Synonyms: IL-15, MGC9721

Related Genes

# Gene Symbol Number of hits
1 CSF3 1 hits
2 CXCL10 1 hits
3 IL17A 1 hits
4 IL1R1 1 hits
5 IL2 1 hits
6 IL2RA 1 hits
7 IL2RB 1 hits
8 IL2RG 1 hits
9 IL4 1 hits
10 IL6 1 hits
11 JAK1 1 hits
12 RAG2 1 hits
13 SYK 1 hits
14 VEGFA 1 hits

Related Sentences

# PMID Sentence
1 32961903 Patients with T2D showed elevated IL-1Ra, IL-6, IL-17A, G-CSF, IP-10, MIP-1α, and bFGF levels; concentrations of IL-4, IL-12, IL-15, INF-γ, and VEGF were decreased.
2 32961903 IL-6, IL-17A, G-CSF, MIP-1α, and bFGF correlated negatively with eGFR; IL-10 and VEGF demonstrated negative associations with WFDC2; no relationships with podocyte markers were found.
3 32961903 Adjusted IL-17A and MIP-1α were predictors of non-albuminuric CKD, IL-13 predicted albuminuria with preserved renal function, meanwhile, IL-6 and hsCRP were predictors of albuminuria with eGFR decline.
4 28111009 Anti-GBM-GN was induced in three strains of immune-deficient mice (Rag2-/-, Rag2-/-Il2rg-/-, and Rag2-/-Il2rb-/-) that are devoid of either T/B cells or T/B/NK cells.
5 28111009 Anti-GBM-GN was induced in three strains of immune-deficient mice (Rag2-/-, Rag2-/-Il2rg-/-, and Rag2-/-Il2rb-/-) that are devoid of either T/B cells or T/B/NK cells.
6 28111009 Anti-GBM-GN was induced in three strains of immune-deficient mice (Rag2-/-, Rag2-/-Il2rg-/-, and Rag2-/-Il2rb-/-) that are devoid of either T/B cells or T/B/NK cells.
7 28111009 Anti-GBM-GN was induced in three strains of immune-deficient mice (Rag2-/-, Rag2-/-Il2rg-/-, and Rag2-/-Il2rb-/-) that are devoid of either T/B cells or T/B/NK cells.
8 28111009 The Rag2-/-Il2rg-/- or Rag2-/-Il2rb-/- mice harbor an additional deletion of either the common gamma chain (γC) or the interleukin-2 receptor β subunit (IL-2Rβ), respectively, impairing IL-15 signaling in particular.
9 28111009 The Rag2-/-Il2rg-/- or Rag2-/-Il2rb-/- mice harbor an additional deletion of either the common gamma chain (γC) or the interleukin-2 receptor β subunit (IL-2Rβ), respectively, impairing IL-15 signaling in particular.
10 28111009 The Rag2-/-Il2rg-/- or Rag2-/-Il2rb-/- mice harbor an additional deletion of either the common gamma chain (γC) or the interleukin-2 receptor β subunit (IL-2Rβ), respectively, impairing IL-15 signaling in particular.
11 28111009 The Rag2-/-Il2rg-/- or Rag2-/-Il2rb-/- mice harbor an additional deletion of either the common gamma chain (γC) or the interleukin-2 receptor β subunit (IL-2Rβ), respectively, impairing IL-15 signaling in particular.
12 28111009 Given that IL-15 has been found highly expressed in nephritic kidneys despite the absence of lymphocytes, we then studied this cytokine in vitro on primary cultured podocytes from immune-deficient mice (Rag2-/-Il2rg-/- and Rag2-/-Il2rb-/-) compared to controls.
13 28111009 Given that IL-15 has been found highly expressed in nephritic kidneys despite the absence of lymphocytes, we then studied this cytokine in vitro on primary cultured podocytes from immune-deficient mice (Rag2-/-Il2rg-/- and Rag2-/-Il2rb-/-) compared to controls.
14 28111009 Given that IL-15 has been found highly expressed in nephritic kidneys despite the absence of lymphocytes, we then studied this cytokine in vitro on primary cultured podocytes from immune-deficient mice (Rag2-/-Il2rg-/- and Rag2-/-Il2rb-/-) compared to controls.
15 28111009 Given that IL-15 has been found highly expressed in nephritic kidneys despite the absence of lymphocytes, we then studied this cytokine in vitro on primary cultured podocytes from immune-deficient mice (Rag2-/-Il2rg-/- and Rag2-/-Il2rb-/-) compared to controls.
16 28111009 IL-15 induced downstream activation of JAK1/3 and SYK in primary cultured podocytes.
17 28111009 IL-15 induced downstream activation of JAK1/3 and SYK in primary cultured podocytes.
18 28111009 IL-15 induced downstream activation of JAK1/3 and SYK in primary cultured podocytes.
19 28111009 IL-15 induced downstream activation of JAK1/3 and SYK in primary cultured podocytes.
20 28111009 IL-15-dependent JAK/SYK induction was impaired in the absence of γC or IL-2Rβ.
21 28111009 IL-15-dependent JAK/SYK induction was impaired in the absence of γC or IL-2Rβ.
22 28111009 IL-15-dependent JAK/SYK induction was impaired in the absence of γC or IL-2Rβ.
23 28111009 IL-15-dependent JAK/SYK induction was impaired in the absence of γC or IL-2Rβ.