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Gene Information
Gene symbol: IRAK4
Gene name: interleukin-1 receptor-associated kinase 4
HGNC ID: 17967
Synonyms: NY-REN-64
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | IL1A | 1 hits |
| 2 | IL1B | 1 hits |
| 3 | IL1R1 | 1 hits |
| 4 | IL1RAPL2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 31974740 | Therapeutic effects of interleukin-1 receptor-associated kinase 4 inhibitor AS2444697 on diabetic nephropathy in type 2 diabetic mice. |
| 2 | 31974740 | Interleukin-1 (IL-1) receptor-associated kinase 4 (IRAK-4) is a pivotal molecule for IL-1 receptor- and Toll-like receptor-induced activation of proinflammatory mediators. |
| 3 | 31974740 | In addition, AS2444697 attenuated plasma levels of proinflammatory cytokines, including IL-6; plasma levels of endothelial dysfunction markers, including intercellular adhesion molecule-1; and plasma levels and renal contents of oxidative stress markers. |
| 4 | 31974740 | Therapeutic effects of interleukin-1 receptor-associated kinase 4 inhibitor AS2444697 on diabetic nephropathy in type 2 diabetic mice. |
| 5 | 31974740 | Interleukin-1 (IL-1) receptor-associated kinase 4 (IRAK-4) is a pivotal molecule for IL-1 receptor- and Toll-like receptor-induced activation of proinflammatory mediators. |
| 6 | 31974740 | In addition, AS2444697 attenuated plasma levels of proinflammatory cytokines, including IL-6; plasma levels of endothelial dysfunction markers, including intercellular adhesion molecule-1; and plasma levels and renal contents of oxidative stress markers. |