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Gene Information
Gene symbol: JMJD6
Gene name: jumonji domain containing 6
HGNC ID: 19355
Synonyms: PTDSR1, KIAA0585
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
23979159
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We report that kidney injury molecule-1 (KIM-1), an epithelial phosphatidylserine receptor expressed transiently after acute injury and chronically in fibrotic renal disease, promotes kidney fibrosis.
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2 |
23979159
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Kim1(RECtg) kidneys had elevated expression of proinflammatory monocyte chemotactic protein-1 (MCP-1) at early time points.
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3 |
23979159
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Heterologous expression of KIM-1 in an immortalized proximal tubule cell line triggered MCP-1 secretion and increased MCP-1-dependent macrophage chemotaxis.
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4 |
23979159
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In mice expressing a mutant, truncated KIM-1 polypeptide, experimental kidney fibrosis was ameliorated with reduced levels of MCP-1, consistent with a profibrotic role for native KIM-1.
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